Plant antimicrobial peptides (AMPs) have evolved differently from AMPs from other life
forms. They are generally rich in cysteine residues which form multiple disulfides. In turn, the …

Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We
include an account of their discovery, characterization, and distribution in the plant kingdom …

Proteases are ubiquitous in nature, whereas naturally occurring peptide ligases, enzymes
catalyzing the reverse reactions of proteases, are rare occurrences. Here we describe the …

The last years have seen a steady increase in our understanding of legumain biology that is
driven from two largely uncoupled research arenas, the mammalian and the plant legumain …

Cyclotides are diverse plant backbone cyclized peptides that have attracted interest as
pharmaceutical scaffolds, but fundamentals of their biosynthetic origin remain elusive …

Breaking and forming peptidyl bonds are fundamental biochemical reactions in protein
chemistry. Unlike proteases that are abundantly available, fast-acting ligases are rare …

The avalanche of genomic information in the past decade has revealed that natural product
biosynthesis using the ribosomal machinery is much more widespread than originally …

Vacuolar processing enzyme (VPE) is a cysteine proteinase originally identified as the
proteinase responsible for the maturation and activation of vacuolar proteins in plants, and it …

Almost all plant cells have large vacuoles that contain both hydrolytic enzymes and a variety
of defense proteins. Plants use vacuoles and vacuolar contents for programmed cell death …