Objective Thyroglobulin measurement is the cornerstone of modern management of
differentiated thyroid cancer, with clinical decisions on treatment and follow-up based on the …

Follicular cell-derived thyroid carcinomas constitute the majority of thyroid malignancies.
This heterogeneous group of tumours includes well differentiated, poorly differentiated, and …

Over the past three decades, laboratory medicine has significantly evolved thanks to
technological advances made possible by new materials and evidence. Clinicians' ongoing …

Background/Objectives: Disease recurrence and resistance to radioiodine (RAI) therapy are
major challenges in the management of differentiated thyroid cancer (DTC). In particular, the …

Thyroglobulin (Tg) is an iodinated glycoprotein, which is normally stored in the follicular
colloid of the thyroid, being a substrate for thyroid hormone production. Since it is produced …

Purpose The management of differentiated thyroid cancer (DTC) is actually based on a
dynamic risk stratification based on classes of response to the therapy. Indeterminate …

Differentiated thyroid carcinoma (DTC) is the most common endocrine cancer and its
incidence has increased in the past decades. Generally, DTC has an indolent course with a …

Context Tumor volume doubling time (TVDT) is emerging as a useful tool in predicting
oncologic outcomes. There are limited data on the prognostic role of TVDT in metastatic …

Abstract Background [18F] FDG PET/CT has been widely used as a diagnostic tool in
detection and localization of recurrent non-avid radioiodine lesions in post-operative …

Differentiated thyroid cancer (DTC) represents the most frequent endocrine neoplasm,
accounting for 5% of thyroid nodules [1]. The standard treatment of patients with DTC …