[HTML][HTML] Live-cell imaging in the deep learning era

JW Pylvänäinen, E Gómez-de-Mariscal… - Current Opinion in Cell …, 2023 - Elsevier
Live imaging is a powerful tool, enabling scientists to observe living organisms in real time.
In particular, when combined with fluorescence microscopy, live imaging allows the …

Prospects of surface-enhanced Raman spectroscopy for biomarker monitoring toward precision medicine

J Plou, PS Valera, I Garcia, CDL de Albuquerque… - ACS …, 2022 - ACS Publications
Future precision medicine will be undoubtedly sustained by the detection of validated
biomarkers that enable a precise classification of patients based on their predicted disease …

Omnipose: a high-precision morphology-independent solution for bacterial cell segmentation

KJ Cutler, C Stringer, TW Lo, L Rappez, N Stroustrup… - Nature …, 2022 - nature.com
Advances in microscopy hold great promise for allowing quantitative and precise
measurement of morphological and molecular phenomena at the single-cell level in …

DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches

C Spahn, E Gómez-de-Mariscal, RF Laine… - Communications …, 2022 - nature.com
This work demonstrates and guides how to use a range of state-of-the-art artificial neural-
networks to analyse bacterial microscopy images using the recently developed …

Towards artificial intelligence-enabled extracellular vesicle precision drug delivery

ZF Greenberg, KS Graim, M He - Advanced Drug Delivery Reviews, 2023 - Elsevier
Abstract Extracellular Vesicles (EVs), particularly exosomes, recently exploded into
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …

High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation

RF Laine, HS Heil, S Coelho, J Nixon-Abell… - Nature …, 2023 - nature.com
Live-cell super-resolution microscopy enables the imaging of biological structure dynamics
below the diffraction limit. Here we present enhanced super-resolution radial fluctuations …

Open microscopy in the life sciences: quo vadis?

J Hohlbein, B Diederich, B Marsikova, EG Reynaud… - Nature …, 2022 - nature.com
Light microscopy enables researchers to observe cellular mechanisms with high spatial and
temporal resolution. However, the increasing complexity of current imaging technologies …

End-to-end reproducible AI pipelines in radiology using the cloud

D Bontempi, L Nuernberg, S Pai… - Nature …, 2024 - nature.com
Artificial intelligence (AI) algorithms hold the potential to revolutionize radiology. However, a
significant portion of the published literature lacks transparency and reproducibility, which …

[HTML][HTML] Advanced optical imaging for the rational design of nanomedicines

A Ortiz-Perez, M Zhang, LW Fitzpatrick… - Advanced Drug Delivery …, 2024 - Elsevier
Despite the enormous potential of nanomedicines to shape the future of medicine, their
clinical translation remains suboptimal. Translational challenges are present in every step of …

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries

E Peuhu, G Jacquemet, CLGJ Scheele, A Isomursu… - Developmental Cell, 2022 - cell.com
Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer. During invasion, the
encapsulating DCIS basement membrane (BM) is compromised, and tumor cells invade the …