Secondary metabolites in fungus-plant interactions

T Pusztahelyi, IJ Holb, I Pócsi - Frontiers in plant science, 2015 - frontiersin.org
Fungi and plants are rich sources of thousands of secondary metabolites. The genetically
coded possibilities for secondary metabolite production, the stimuli of the production, and …

Ten decadal advances in fungal biology leading towards human well-being

A Mapook, KD Hyde, K Hassan, BM Kemkuignou… - Fungal Diversity, 2022 - Springer
Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

Diversity, application, and synthetic biology of industrially important Aspergillus fungi

HS Park, SC Jun, KH Han, SB Hong, JH Yu - Advances in applied …, 2017 - Elsevier
The filamentous fungal genus Aspergillus consists of over 340 officially recognized species.
A handful of these Aspergillus fungi are predominantly used for food fermentation and large …

From axenic to mixed cultures: technological advances accelerating a paradigm shift in microbiology

C Nai, V Meyer - Trends in microbiology, 2018 - cell.com
Since the onset of microbiology in the late 19th century, scientists have been growing
microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …

Chemodiversity in the genus Aspergillus

JC Frisvad, TO Larsen - Applied Microbiology and Biotechnology, 2015 - Springer
Isolates of Aspergillus species are able to produce a large number of secondary
metabolites. The profiles of biosynthetic families of secondary metabolites are species …

Enzymatic dimerization in the biosynthetic pathway of microbial natural products

J Liu, A Liu, Y Hu - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to August 2020 The dramatic increase in the identification of dimeric natural
products generated by microorganisms and plants has played a significant role in drug …

An overview on the biological activity and anti-cancer mechanism of lovastatin

L Xie, G Zhu, J Shang, X Chen, C Zhang, X Ji, Q Zhang… - Cellular …, 2021 - Elsevier
Lovastatin, a secondary metabolite isolated from fungi, is often used as a representative
drug to reduce blood lipid concentration and treat hypercholesterolemia. Its structure is …

Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological …

NK Mund, E Čellárová - Biotechnology Advances, 2023 - Elsevier
Natural anthraquinones are represented by a large group of compounds. Some of them are
widespread across the kingdoms, especially in bacteria, fungi and plants, while the others …

Aspergillus terreus species complex

C Lass-Flörl, AM Dietl, DP Kontoyiannis… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …

Recent advances in the genome mining of Aspergillus secondary metabolites (covering 2012–2018)

J Romsdahl, CCC Wang - Medchemcomm, 2019 - pubs.rsc.org
Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …