An important approach in tumor therapy is combining substances with different action
mechanisms aiming to enhance the antineoplastic effect, decrease the therapeutic dosage …

Canine tumors are valuable comparative models for human counterparts, especially to
explore novel biomarkers and to understand pathways and processes involved in …

Canine prostate cancer is classified into adenocarcinoma, transitional cell carcinoma with
prostatic involvement, and mixed forms. Early metastatic spread leads to poor prognosis and …

Simple Summary Mammary gland tumors are most frequent in non-castrated female dogs
and represent an interesting model for understanding tumor biology of human breast cancer …

The use of tyrosine kinase inhibitors (TKI) has been growing in veterinary oncology and in
the past few years several TKI have been tested in dogs. However, different from human …

Background Vascular endothelial growth factor‐A (VEGF‐A) and its receptor, VEGF receptor‐
2 (VEGFR‐2), represent a complex family of angiogenic molecules consisting of different …

Simple Summary Prostate cancer is one of the leading causes of cancer deaths worldwide,
even when found early in the disease, in both humans and dogs. Prostate cancer in dogs is …

Vasculogenic mimicry (VM) is the ability of highly aggressive cancer cells to form fluid-
conducting channels that facilitate the nutrition and metastasis of cancer cells. Considering …

O carcinoma de próstata é o segundo tipo de neoplasia maligna mais comum entre os
homens no Brasil, e relatado em cães entre 8 a 10 anos de idade, com rápida evolução …