Sjögren's syndrome: a systemic autoimmune disease

S Negrini, G Emmi, M Greco, M Borro… - Clinical and …, 2022 - Springer
Sjögren's syndrome is a chronic autoimmune disease characterized by ocular and oral
dryness resulting from lacrimal and salivary gland dysfunction. Besides, a variety of systemic …

Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies

GE Thorlacius, A Björk… - Nature Reviews …, 2023 - nature.com
In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies

M Ramos-Casals, P Brito-Zerón… - Annals of the …, 2020 - ard.bmj.com
The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in
recent decades: treatment decisions remain challenging in clinical practice, without a …

Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment

FB Vivino, VY Bunya… - Clinical …, 2019 - pubmed.ncbi.nlm.nih.gov
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …

Update on the pathophysiology and treatment of primary Sjögren syndrome

C Baldini, G Fulvio, G La Rocca, F Ferro - Nature Reviews …, 2024 - nature.com
Sjögren syndrome or Sjögren disease is a chronic form of autoimmune epithelitis
characterized by lymphocytic infiltration of the exocrine glands, particularly the salivary and …

[HTML][HTML] Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus

TA van der Meulen, HJM Harmsen, AV Vila… - Journal of …, 2019 - Elsevier
Objective Alterations in the microbiota composition of the gastro-intestinal tract are
suspected to be involved in the etiopathogenesis of two closely related systemic …

How immunological profile drives clinical phenotype of primary Sjogren's syndrome at diagnosis: analysis of 10,500 patients (Sjogren Big Data Project)

P Brito-Zerón, N Acar-Denizli, WF Ng… - Clinical and …, 2018 - research.rug.nl
Objective. To evaluate the influence of the main immunological markers on the disease
phenotype at diagnosis in a large international cohort of patients with primary Sjogren's …

Epidemiology of Sjögren syndrome

M Beydon, S McCoy, Y Nguyen, T Sumida… - Nature Reviews …, 2024 - nature.com
Sjögren syndrome is a phenotypically varied autoimmune disorder that can occur alone in
primary Sjögren syndrome or in association with other connective tissue diseases (CTDs) …

Clinical and immunological parameters of Sjögren's syndrome

K Psianou, I Panagoulias, AD Papanastasiou… - Autoimmunity …, 2018 - Elsevier
Sjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine
glands, resulting in their functional impairment. In SS, lymphocytic infiltration of salivary and …

Ocular manifestations in rheumatoid arthritis, connective tissue disease, and vasculitis: a systematic review and metaanalysis

MA Turk, JL Hayworth, T Nevskaya… - The Journal of …, 2021 - jrheum.org
Objective. Rheumatoid arthritis (RA) and other rheumatic diseases may present with ocular
manifestations. The purpose of our work was to determine the prevalence and type of eye …