Assessing clinical potential of old antibiotics against severe infections by multi-drug-resistant gram-negative bacteria using in silico modelling

P Paranos, S Vourli, S Pournaras, J Meletiadis - Pharmaceuticals, 2022 - mdpi.com
In the light of increasing antimicrobial resistance among gram-negative bacteria and the lack
of new more potent antimicrobial agents, new strategies have been explored. Old antibiotics …

Exploring the Role of Boron-Containing Compounds in Biological Systems: Potential Applications and Key Challenges

H Khaliq - Journal of Trace Elements in Medicine and Biology, 2025 - Elsevier
Background Boron, a naturally abundant trace element, plays a crucial role in various
biological processes and influences important physiological functions such as bone health …

Environmental risk control of florfenicol in water: From technology selection to mechanism discussion

W Wang, J Li, M Fang, Y Chang, T Wang… - Journal of …, 2024 - Elsevier
Florfenicol (FLO) is the most widely used veterinary antibiotic and has been detected
frequently in various animal products and water bodies. Electrooxidation and …

Preparation and Characteristics of Tildipirosin-Loaded Solid Lipid Nanoparticles for the Treatment of Intracellular Staphylococcus aureus Infections

Z Lei, X Cai, Z Li, T Sun - Biomaterials Science, 2025 - pubs.rsc.org
To enhance the antibacterial efficacy of tildipirosin against Staphylococcus aureus (SA)
infections, optimized solid lipid nanoparticles loaded with tildipirosin (SLN-TD) were …

[HTML][HTML] In vivo pharmacokinetic and pharmacodynamic study and cutoff of florfenicol against Riemerella anatipestifer in ducks

HL Zhang, FL Li, HY Chen, DM Qin, SJ Sun, MM Zhang… - Poultry Science, 2025 - Elsevier
Riemerella anatipestifer causes serious infections, characterized by septicemia and
serositis, in ducks and geese. R. anatipestifer is mainly controlled through antimicrobial …

A Green HPLC Approach to Florfenicol Analysis in Pig Urine

K Šandor, E Perak Junaković, S Terzić, I Žarković… - Pharmaceuticals, 2024 - mdpi.com
Florfenicol (FF) is a broad-spectrum antibiotic used to treat gastrointestinal and respiratory
infections in domestic animals. Considering FF's rapid elimination via urine after drug …

Antibacterial activity of combined aditoprim and sulfamethoxazole against Escherichia coli from swine and a dose regimen based on pharmacokinetic …

F Wang, W Luo, Y Pan, W Qu, S Xie… - Journal of Veterinary …, 2022 - Wiley Online Library
The mortality of livestock caused by pathogenic Escherichia coli (E. coli) still accounts for a
large proportion of deaths in large‐scale production and reproduction, which causes …

[HTML][HTML] Research Note: Epidemiological cutoff values and acquired resistance mechanisms of three veterinary antibiotics against Escherichia coli from chicken …

HL Zhang, SL Wu, JL Fu, HX Jiang, HZ Ding - Poultry Science, 2021 - Elsevier
Florfenicol, apramycin, and danofloxacin are antibiotics approved only for veterinary use
and that have good therapeutic effects on chicken respiratory infections caused by …

30 mg/kg dózisban, intramuszkulárisan alkalmazott florfenikol farmakokinetikai tulajdonságai sertés ízületi folyadékban és PK/PD integrációja Streptococcus suis ellen

R Simon - 2022 - huveta.hu
A florfenikol a fenikolok csoportjába tartozó kis molekulatömegű, széles antibakteriális
spektrummal rendelkező hatóanyag, amely a Gram-pozitív és a Gram-negatív …