DNA repair pathways in breast cancer: from mechanisms to clinical applications
M Tufail - Breast Cancer Research and Treatment, 2023 - Springer
Background Breast cancer (BC) is a complex disease with various subtypes and genetic
alterations that impact DNA repair pathways. Understanding these pathways is essential for …
alterations that impact DNA repair pathways. Understanding these pathways is essential for …
Exploring RAD18-dependent replication of damaged DNA and discontinuities: a collection of advanced tools
DNA damage tolerance (DDT) pathways mitigate the effects of DNA damage during
replication by rescuing the replication fork stalled at a DNA lesion or other barriers and also …
replication by rescuing the replication fork stalled at a DNA lesion or other barriers and also …
A comprehensive analysis of Fanconi anemia genes in Chinese patients with high-risk hereditary breast cancer
QY Zhu, PC Li, YF Zhu, JN Pan, R Wang, XL Li… - Journal of Cancer …, 2023 - Springer
Abstract Background Four Fanconi anemia (FA) genes (BRCA1, BRCA2, PALB2 and
RAD51C) are defined as breast cancer (BC) susceptibility genes. Other FA genes have …
RAD51C) are defined as breast cancer (BC) susceptibility genes. Other FA genes have …
Global trends in BRCA-related breast cancer research from 2013 to 2022: A scientometric analysis
Y Huang, D Zheng, Q Yang, J Wu, H Tian, Z Ji… - Frontiers in …, 2023 - frontiersin.org
Introduction Since the mid-2000s, breast cancer incidence among women has slowly
increased at about 0.5% per year. In the last three decades, Breast Cancer Susceptibility …
increased at about 0.5% per year. In the last three decades, Breast Cancer Susceptibility …
Mutated FANCA Gene Role in the Modulation of Energy Metabolism and Mitochondrial Dynamics in Head and Neck Squamous Cell Carcinoma
Fanconi Anaemia (FA) is a rare recessive genetic disorder characterized by a defective DNA
repair mechanism. Although aplastic anaemia is the principal clinical sign in FA, patients …
repair mechanism. Although aplastic anaemia is the principal clinical sign in FA, patients …
Banoxantrone Coordinated Metal− Organic Framework for Photoacoustic Imaging‐Guided High Intensity Focused Ultrasound Therapy
T Sun, J Li, C Zeng, C Luo, X Luo… - Advanced Healthcare …, 2023 - Wiley Online Library
Photoacoustic (PA) imaging with high spatial resolution has great potential as desired
monitoring means in the high‐intensity focused ultrasound (HIFU) surgery of tumor …
monitoring means in the high‐intensity focused ultrasound (HIFU) surgery of tumor …
Clinical relevance of double heterozygosity revealed by next-generation sequencing of homologous recombination repair pathway genes in South African breast …
NC van der Merwe, I Buccimazza, B Rossouw… - Breast Cancer Research …, 2024 - Springer
Purpose Genetically predisposed breast cancer (BC) patients represent a minor but
clinically meaningful subgroup of the disease, with 25% of all cases associated with …
clinically meaningful subgroup of the disease, with 25% of all cases associated with …
Individual Radiation Sensitivity and Biomarkers: Molecular Radiation Biology
In recent years, scientific understanding of the changes radiation makes to the various
tissues of the body has vastly increased. Identification of biological markers of radiation …
tissues of the body has vastly increased. Identification of biological markers of radiation …
Geni di suscettibilità al carcinoma ereditario della mammella.
I Veneruso, C Scarano, V D'Argenio - Biochimica Clinica, 2023 - search.ebscohost.com
Hereditary breast cancers account for about 10% of all breast cancers. Nevertheless, the
early and correct identification of these forms is crucial for patients' management and risk …
early and correct identification of these forms is crucial for patients' management and risk …