Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Vitamin D insufficiency or deficiency (VDD) is a very prevalent condition in the general
population. Vitamin D is necessary for optimal bone mineralization, but apart from the bone …

This article highlights new members, novel mechanisms of action, new functions, and
interesting applications of antimicrobial peptides reported in 2014. As of December 2014 …

Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates.
While their antibacterial activity toward bacterial cells was the original focus for research …

As the incidence of diabetes continues to increase in the western world, the prevalence of
chronic wounds related to this condition continues to be a major focus of wound care …

Antimicrobial peptides (AMPs) is a large family of compounds serving as natural antibiotics,
widely distributed across the organism, mainly in mucus layers. They are designed to …

Studies described so far suggest that human β-defensin 2 is an important protein of innate
immune response which provides protection for the human organism against invading …

Diabetic foot infection (DFI) management requires complex multidisciplinary care pathways
with off-loading, debridement and targeted antibiotic treatment central to positive clinical …

Diabetic foot ulcer (DFU) is a devastating complication, affecting around 15% of diabetic
patients and representing a leading cause of non-traumatic amputations. Notably, the risk of …