Novel bio-therapeutic agents that harness the properties of small, non-coding nucleic acids
hold great promise for clinical applications. These include antisense oligonucleotides that …

Long noncoding RNAs (lncRNAs) are a class of noncoding transcripts characterized with
more than 200 nucleotides of length. Unlike their names, some short open reading frames …

Eukaryotic genomes encode thousands of RNA molecules; however, only a minimal fraction
is translated into proteins. Among the non-coding elements, long non-coding RNAs …

Protein stability and turnover is critical in normal cellular and physiological process and their
misregulation may contribute to accumulation of unwanted proteins causing cellular …

The cells of the intestinal epithelium establish the frontline for host defense against
pathogens in the gastrointestinal tract and play a vital role in the initiation of the immune …

The discovery of functional long non-coding RNAs (lncRNAs) changed their initial concept
as transcriptional noise. LncRNAs have been identified as regulators of multiple biological …

While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …

Long non-coding RNAs (lncRNAs) have emerged as auxiliary regulators of gene expression
influencing tumor microenvironment, metastasis and radio-resistance in cancer. The …

The sterility or inviability of hybrid offspring produced from an interspecific mating result from
incompatibilities between parental genotypes that are thought to result from divergence of …

Long non-coding RNAs (lncRNAs) are highly expressed and can modulate multiple cellular
processes including transcription, splicing, translation, and many diverse signaling events …