Natural killer (NK) cells serve as a first line of defense against acute viral infections.
Immunogenetic association data suggest that NK cells also influence the course of chronic …

Background: Coronary artery disease is an incurable, life-threatening disease that was once
considered primarily a disorder of lipid deposition. Coronary artery disease is now also …

In this review, we discuss how IgG antibodies can modulate inflammatory signaling during
viral infections with a focus on CD16a‐mediated functions. We describe the structural …

Immunotherapy using immune checkpoint inhibitors (ICIs) induces durable responses in
many metastatic cancers. Metastatic uveal melanoma (mUM), typically occurring in the liver …

Severe COVID-19 is linked to both dysfunctional immune response and unrestrained
immunopathology, and it remains unclear whether T cells contribute to disease pathology …

Chimeric antigen receptor (CAR) T cell therapy is effective in treating B cell malignancies,
but factors influencing the persistence of functional CAR+ T cells, such as product …

Human cytomegalovirus (HCMV) infection is an important cause of morbidity and mortality in
transplant recipients. Long-term protective immunity against HCMV requires both sustained …

The mechanisms underlying the immune remodeling and severity response in coronavirus
disease 2019 (COVID-19) are yet to be fully elucidated. Our comprehensive integrative …

Invariant NKT cells are important in the activation and regulation of immune responses. They
can also function as CD1d‐restricted killer cells. However, the role of activating innate NK …

Chronic immune activation is a driver of human immunodeficiency virus type 1 (HIV-1)
disease progression. Here, we describe that subjects with chronic hepatitis C virus …