The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

Pregnancy poses an immunological challenge because a genetically distinct (nonself) fetus
must be supported within the pregnant female for the required gestational period …

Mononuclear phagocyte plasticity includes the expression of functions related to the
resolution of inflammation, tissue repair and remodelling, particularly when these cells are …

The maternal-fetal interface undergoes dynamic changes to allow the fetus to grow and
develop in the uterus, despite being recognized by the maternal immune cells. Within the …

The presence of immune cells in the placental bed is important for both mother and child.
Although various immune cells can be found in the placental bed, such as regulatory T cells …

Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …

A successful pregnancy requires that the maternal immune system is instructed to a state of
tolerance to avoid rejection of the semiallogeneic fetal–placental unit. Although increasing …

Macrophages perform many specific functions including host defense, homeostasis,
angiogenesis, and tissue development. Macrophages are the second most abundant …

During pregnancy, the maternal immune system is challenged by the presence of the fetus,
which must be tolerated despite being semiallogeneic. Uterine mucosal (or decidual) …

Preeclampsia is an important complication in pregnancy, characterized by hypertension and
proteinuria in the second half of pregnancy. Generalized activation of the inflammatory …