Cerebral small vessel disease and the risk of dementia: a systematic review and meta-analysis of population-based evidence

D Bos, FJ Wolters, SKL Darweesh, MW Vernooij… - Alzheimer's & …, 2018 - Elsevier
Introduction Cerebral small vessel disease is increasingly linked to dementia. Methods We
systematically searched Medline, Embase, and Cochrane databases for prospective …

White matter hyperintensities volume and cognition: A meta-analysis

W Guo, J Shi - Frontiers in aging neuroscience, 2022 - frontiersin.org
Background Cerebral small vessel disease (CSVD) is prevalent in the elderly and leads to
an increased risk of cognitive impairment and dementia. The volume of white matter …

Location sensitive deep convolutional neural networks for segmentation of white matter hyperintensities

M Ghafoorian, N Karssemeijer, T Heskes… - Scientific Reports, 2017 - nature.com
The anatomical location of imaging features is of crucial importance for accurate diagnosis
in many medical tasks. Convolutional neural networks (CNN) have had huge successes in …

Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure

EH Wilker, SR Preis, AS Beiser, PA Wolf, R Au, I Kloog… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Long-term exposure to ambient air pollution is associated with
cerebrovascular disease and cognitive impairment, but whether it is related to structural …

Association of nonalcoholic fatty liver disease with lower brain volume in healthy middle-aged adults in the Framingham study

G Weinstein, S Zelber-Sagi, SR Preis, AS Beiser… - JAMA …, 2018 - jamanetwork.com
Importance Nonalcoholic fatty liver disease (NAFLD) is a common condition that is most
often asymptomatic. It is associated with metabolic syndrome, incident diabetes, carotid …

Association between slow-wave sleep loss and incident dementia

JJ Himali, AA Baril, MG Cavuoto, S Yiallourou… - JAMA …, 2023 - jamanetwork.com
Importance Slow-wave sleep (SWS) supports the aging brain in many ways, including
facilitating the glymphatic clearance of proteins that aggregate in Alzheimer disease …

Non‐alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle‐aged adults: The Framingham Study

G Weinstein, K Davis‐Plourde, JJ Himali… - Liver …, 2019 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) is common and has been recently
related to brain health. We aimed to assess the relationships of NAFLD and its severity …

Imaging markers of brain frailty and outcome in patients with acute ischemic stroke

N Bu, MS Khlif, R Lemmens, A Wouters, JB Fiebach… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Functional outcome after stroke may be related to preexisting
brain health. Several imaging markers of brain frailty have been described including brain …

A systematic review of longitudinal studies which measure Alzheimer's disease biomarkers

E Lawrence, C Vegvari, A Ower… - Journal of …, 2017 - content.iospress.com
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease, with no
effective treatment or cure. A gold standard therapy would be treatment to slow or halt …

Cognitive impairment and risk of stroke: a systematic review and meta-analysis of prospective cohort studies

S Rostamian, S Mahinrad, T Stijnen, B Sabayan… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Cognitive impairment is linked to vascular risk factors and brain
vascular pathologies. Several studies have tested whether subjects with cognitive …