Frontiers of sodium MRI revisited: from cartilage to brain imaging

O Zaric, V Juras, P Szomolanyi… - Journal of Magnetic …, 2021 - Wiley Online Library
Sodium magnetic resonance imaging (23Na‐MRI) is a highly promising imaging modality
that offers the possibility to noninvasively quantify sodium content in the tissue, one of the …

[HTML][HTML] Recent technical developments and clinical research applications of sodium (23Na) MRI

LV Gast, T Platt, AM Nagel, T Gerhalter - Progress in Nuclear Magnetic …, 2023 - Elsevier
Sodium is an essential ion that plays a central role in many physiological processes
including the transmembrane electrochemical gradient and the maintenance of the body's …

X‐nuclei imaging: Current state, technical challenges, and future directions

R Hu, D Kleimaier, M Malzacher… - Journal of Magnetic …, 2020 - Wiley Online Library
1H imaging is concerned with contrast generation among anatomically distinct soft tissues. X‐
nuclei imaging, on the other hand, aims to reveal the underlying changes in the …

Potential of sodium MRI as a biomarker for neurodegeneration and neuroinflammation in multiple sclerosis

K Huhn, T Engelhorn, RA Linker, AM Nagel - Frontiers in neurology, 2019 - frontiersin.org
In multiple sclerosis (MS), experimental and ex vivo studies indicate that pathologic intra-
and extracellular sodium accumulation may play a pivotal role in inflammatory as well as …

Multinuclear MRI at ultrahigh fields

SC Niesporek, AM Nagel, T Platt - Topics in Magnetic Resonance …, 2019 - journals.lww.com
In this article, an overview of the current developments and research applications for non-
proton magnetic resonance imaging (MRI) at ultrahigh magnetic fields (UHFs) is given. Due …

Comparison of optimized intensity correction methods for 23Na MRI of the human brain using a 32-channel phased array coil at 7 Tesla

S Lachner, L Ruck, SC Niesporek… - … für Medizinische Physik, 2020 - Elsevier
Purpose To correct for the non-homogeneous receive profile of a phased array head coil in
sodium magnetic resonance imaging (23 Na MRI). Methods 23 Na MRI of the human brain …

Assessing muscle‐specific potassium concentrations in human lower leg using potassium magnetic resonance imaging

LV Gast, LM Baier, O Chaudry, CR Meixner… - NMR in …, 2023 - Wiley Online Library
Noninvasively assessing tissue potassium concentrations (TPCs) using potassium magnetic
resonance imaging (39K MRI) could give valuable information on physiological processes …

Quantitative 1H and 23Na muscle MRI in Facioscapulohumeral muscular dystrophy patients

T Gerhalter, B Marty, LV Gast, K Porzelt, R Heiss… - Journal of …, 2021 - Springer
Objective Our aim was to assess the role of quantitative 1 H and 23 Na MRI methods in
providing imaging biomarkers of disease activity and severity in patients with …

Clinically feasible B1 field correction for multi‐organ sodium imaging at 3 T

M Vaeggemose, RF Schulte, C Laustsen - NMR in Biomedicine, 2023 - Wiley Online Library
Sodium MRI allows the non‐invasive quantification of intra‐organ sodium concentration. RF
inhomogeneity introduces uncertainty in this estimated concentration. B1 field corrections …

Sodium Triple Quantum MR Signal Extraction Using a Single‐Pulse Sequence with Single Quantum Time Efficiency

S Reichert, V Schepkin, D Kleimaier… - Magnetic …, 2024 - Wiley Online Library
Purpose Sodium triple quantum (TQ) signal has been shown to be a valuable biomarker for
cell viability. Despite its clinical potential, application of Sodium TQ signal is hindered by …