[HTML][HTML] Mediators and mechanisms of heat shock protein 70 based cytoprotection in obstructive nephropathy
L Mazzei, NG Docherty, W Manucha - Cell Stress and Chaperones, 2015 - Elsevier
Urinary heat shock protein 70 (Hsp70) is rapidly increased in patients with clinical acute
kidney injury, indicating that it constitutes a component of the endogenous stress response …
kidney injury, indicating that it constitutes a component of the endogenous stress response …
Growing evidence suggests WT1 effects in the kidney development are modulated by Hsp70/NO interaction
L Mazzei, W Manucha - Journal of Nephrology, 2017 - Springer
The study of kidney development at the cellular and molecular levels remains an active area
of nephrology research. The functional integrity of the kidney depends on normal …
of nephrology research. The functional integrity of the kidney depends on normal …
WT-1 mRNA expression is modulated by nitric oxide availability and Hsp70 interaction after neonatal unilateral ureteral obstruction
L Mazzei, IM García, V Cacciamani, ME Benardón… - Biocell, 2010 - SciELO Argentina
Wilms tumor gene 1 (wt-1), a key regulator of mesenchymal-epithelial transformation, is
downregulated during congenital obstructive nephropathy, leading to apoptosis. There is a …
downregulated during congenital obstructive nephropathy, leading to apoptosis. There is a …
Wt‐1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive Nephropathy
L Mazzei, W Manucha - Advances in Urology, 2013 - Wiley Online Library
The wt-1 gene encodes a zinc finger DNA‐binding protein that acts as a transcriptional
activator or repressor depending on the cellular or chromosomal context. The wt-1 regulates …
activator or repressor depending on the cellular or chromosomal context. The wt-1 regulates …
Alterations on a key nephrogenic/cardiogenic gene expression linked to hypertension development
L Mazzei, R Sanz, W Manucha - Clínica e Investigación en Arteriosclerosis …, 2020 - Elsevier
The elevation of blood pressure produces specific organic lesions, including kidney and
cardiac damage. On the other hand, cardiovascular disease usually leads to the …
cardiac damage. On the other hand, cardiovascular disease usually leads to the …
Characterization of Wilms' Tumour 1 (Wt1) as a Biomarker for Fibrosis in Duchenne Muscular Dystrophy
P Murphy - 2019 - search.proquest.com
Duchenne muscular dystrophy (DMD) is the most common inherited pediatric muscle
dystrophy. It is characterized by muscle degeneration, resulting in fibrosis that is a significant …
dystrophy. It is characterized by muscle degeneration, resulting in fibrosis that is a significant …
[PDF][PDF] Role of WT1 in Ischaemic Angiogenesis
RJ Ogley - 2018 - core.ac.uk
Ischaemia causes irreversible tissue damage in cardiovascular disease. Since regenerative
angiogenesis fails to consistently induce sufficient reperfusion to facilitate repair, targeted …
angiogenesis fails to consistently induce sufficient reperfusion to facilitate repair, targeted …
Exprese WT1 a jeho sestřihových variant v myeloidních leukémiích
T Macháčková Lopotová - 2017 - dspace.cuni.cz
Myeloidní leukémie představují maligní onemocnění charakterizovaná expanzí myeloidní
krevní řady. Zatímco v případě chronické myeloidní leukémie (CML) je hlavní příčina …
krevní řady. Zatímco v případě chronické myeloidní leukémie (CML) je hlavní příčina …
[PDF][PDF] Luciana Jorgelina MAZZEI1, 3, Walter MANUCHA2, 3 1-Instituto de Genética, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo 2-Área de …
RIDLAN OBSTRUCTIVA - academia.edu
El estudio del desarrollo renal sirve como un paradigma para comprender los mecanismos
que son la base de la formación de un órgano. Múltiples genes desempeñan funciones …
que son la base de la formación de un órgano. Múltiples genes desempeñan funciones …
Exprese WT1 a jeho sestřihových variant v myeloidních leukémiích
T Lopotová - 2013 - dspace.cuni.cz
Myeloidní leukémie představují maligní onemocnění charakterizovaná expanzí myeloidní
krevní řady. Zatímco v případě chronické myeloidní leukémie (CML) je hlavní příčina …
krevní řady. Zatímco v případě chronické myeloidní leukémie (CML) je hlavní příčina …