Exosome and virus infection

Y Peng, Y Yang, Y Li, T Shi, Y Luan, C Yin - Frontiers in Immunology, 2023 - frontiersin.org
Exosomes are messengers of intercellular communication in monolayer vesicles derived
from cells. It affects the pathophysiological process of the body in various diseases, such as …

Pathogenesis and mechanisms of SARS-CoV-2 infection in the intestine, liver, and pancreas

Z Khreefa, MT Barbier, AR Koksal, G Love, L Del Valle - Cells, 2023 - mdpi.com
The novel coronavirus, SARS-CoV-2, rapidly spread worldwide, causing an ongoing global
pandemic. While the respiratory system is the most common site of infection, a significant …

Viruses and autophagy: bend, but don't break

A Jassey, WT Jackson - Nature Reviews Microbiology, 2024 - nature.com
Autophagy is a constitutive cellular process of degradation required to maintain homeostasis
and turn over spent organelles and aggregated proteins. For some viruses, the process can …

[HTML][HTML] Small extracellular vesicles carrying reovirus, tumor antigens, interferon-β, and damage-associated molecular patterns for efficient tumor treatment

N Shuwari, C Inoue, I Ishigami, K Jingushi… - Journal of Controlled …, 2024 - Elsevier
Small extracellular vesicles (SEV) have attracted much attention both as mediators of
intercellular communication and as drug delivery systems. In addition, recent studies have …

Exosome–Autophagy Crosstalk in Enveloped Virus Infection

Y Wang, L Ren, H Bai, Q Jin, L Zhang - International journal of molecular …, 2023 - mdpi.com
Exosomes, which are extracellular vesicles (EVs) predominantly present in bodily fluids,
participate in various physiological processes. Autophagy, an intracellular degradation …

Interactions between endoplasmic reticulum stress and extracellular vesicles in multiple diseases

J Ye, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Immune responses can severely perturb endoplasmic reticulum (ER) function. As a protein-
folding factory and dynamic calcium storage compartment, the ER plays a pivotal role in …

Impaired autophagy in krabbe disease: the role of BCL2 and beclin-1 phosphorylation

N Papini, R Todisco, P Giussani, M Dei Cas… - International Journal of …, 2023 - mdpi.com
Autophagic impairment was identified in many lysosomal storage diseases and adult
neurodegenerative diseases. It seems that this defect could be directly related to the …

Dual roles and potential applications of exosomes in HCV infections

Y Yin, Y Zhao, Q Chen, Y Chen, L Mao - Frontiers in Microbiology, 2022 - frontiersin.org
The hepatitis C virus (HCV) causes severe liver diseases, including hepatitis, liver cirrhosis,
and hepatocellular carcinoma, which have high morbidity and mortality. Antibody targeting …

Plasma Pattern of Extracellular Vesicles Isolated from Hepatitis C Virus Patients and Their Effects on Human Vascular Endothelial Cells

E Grossini, C Smirne, S Venkatesan, S Tonello… - International Journal of …, 2023 - mdpi.com
Hepatitis C virus (HCV) patients are at increased risk of cardiovascular disease (CVD). In
this study, we aimed to evaluate the role of extracellular vesicles (EVs) as pathogenic factors …

HCV egress–unconventional secretion of assembled viral particles

M Bunz, M Ritter, M Schindler - Trends in microbiology, 2022 - cell.com
It is believed that hepatitis C virus (HCV) particles are released through the canonical
secretory route: from the endoplasmic reticulum (ER), via the Golgi, to the plasma …