Orally delivered solid lipid nanoparticles of irinotecan coupled with chitosan surface modification to treat colon cancer: preparation, in-vitro and in-vivo evaluations
NA Bhaskaran, SR Jitta, SP Cheruku, N Kumar… - International Journal of …, 2022 - Elsevier
Irinotecan-loaded solid lipid nanoparticles (IRI-SLNs) was formulated and tested for its
potential activity against colon cancer. IRI-SLNs were prepared by applying the principles of …
potential activity against colon cancer. IRI-SLNs were prepared by applying the principles of …
A new validated facile HPLC analysis method to determine methylprednisolone including its derivatives and practical application
MF Al-Hakkani - Scientific Reports, 2023 - nature.com
Methylprednisolone sodium succinate (MPSS) is a parenteral water-soluble corticosteroid
ester. It gives three peaks methylprednisolone (MP), 17-methylprednisolone hemisuccinate …
ester. It gives three peaks methylprednisolone (MP), 17-methylprednisolone hemisuccinate …
Cefoperazone rapidly and sensitive quantitative assessment via a validated RP-HPLC method for different dosage forms, in-use stability, and antimicrobial activities
MF Al-Hakkani, N Ahmed, AA Abbas, MHA Hassan - BMC chemistry, 2023 - Springer
Cefoperazone (Cfz) is a member of the third generation of parenteral cephalosporin
antibiotics. It is used on a wide scale in prescribed antibiotic drugs as anti-infection …
antibiotics. It is used on a wide scale in prescribed antibiotic drugs as anti-infection …
Implementation of quality by design in the formulation and development of nanocarrier-based drug delivery systems
S Mehrotra, L Kumar - Critical Reviews™ in Therapeutic …, 2023 - dl.begellhouse.com
Quality by design (QbD) has recently fascinated researchers for utilizing it in various arenas
of pharma trends. By overcoming the conventional process, QbD prevents the risk of errors …
of pharma trends. By overcoming the conventional process, QbD prevents the risk of errors …
Analytical 'Quality-by-Design'paradigm in development of a RP-HPLC method for the estimation of cilnidipine in nanoformulations: Forced degradation studies and …
SM Marques, RK Shirodkar, L Kumar - Microchemical Journal, 2023 - Elsevier
The present study focuses on optimizing, developing, and validating a sensitive and specific
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …
Rapid Analytical Method Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Exemestane and Genistein with Specific Application in …
Exemestane (EXE), an irreversible aromatase inhibitor, is employed as a therapy for
hormone-dependent breast cancer. Several studies have also established the budding …
hormone-dependent breast cancer. Several studies have also established the budding …
A comprehensive review on QbD driven analytical procedures developed for the analysis of various drugs
Quality has been a prime priority for the pharmaceutical sector with the development of
recommendations by regulatory organizations like ICH. Concepts of ICH Q8 to Q10 are the …
recommendations by regulatory organizations like ICH. Concepts of ICH Q8 to Q10 are the …
Quantification of suvorexant in human urine using a validated HPTLC bioanalytical method
Suvorexant (SUV) is a new sedative/hypnotic medicine that is recommended to treat
insomnia. It is an important medicine from a forensic point of view due to its …
insomnia. It is an important medicine from a forensic point of view due to its …
Quality-by-design driven analytical method (AQbD) development and validation of HPLC–UV technique to quantify rivastigmine hydrogen tartrate in lipidic …
L Kumar - Microchemical Journal, 2023 - Elsevier
The main purpose of current investigation was to design and further validate a technique for
the quantitative determination of rivastigmine hydrogen tartrate (RHT), a cholinesterase …
the quantitative determination of rivastigmine hydrogen tartrate (RHT), a cholinesterase …
Preparation, characterization and in vivo pharmacokinetic study of ginsenoside Rb1-PLGA nanoparticles
L Du, H Lu, Y Xiao, Z Guo, Y Li - Scientific Reports, 2023 - nature.com
This study aimed to construct a Ginsenoside Rb1-PLGA nano drug delivery system, optimize
its preparation process, characterize and evaluate the resulting Ginsenoside Rb1-PLGA …
its preparation process, characterize and evaluate the resulting Ginsenoside Rb1-PLGA …