The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the
deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the …

Cholesterol is essential for neuronal physiology, both during development and in the adult
life: as a major component of cell membranes and precursor of steroid hormones, it …

New components and functions of the renin‐angiotensin system (RAS) are still being
unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin …

The classic renin–angiotensin system (RAS) was initially described as a hormone system
designed to mediate cardiovascular and body water regulation, with angiotensin II as its …

Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

Although the renin-angiotensin system (RAS) was classically considered as a circulating
system that regulates blood pressure, many tissues are now known to have a local RAS …

A bidirectional relationship exists between hypertension and psychiatric disorders, including
unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis …

Epidemiological studies suggest a positive correlation between the incidence and severity of
multiple sclerosis (MS) and the intake of fatty acids. It remains to be clarified whether high fat …

While it is now well established that the independent brain renin–angiotensin system (RAS)
has some important central functions besides the vascular ones, the relevance of its main …