Somlyo, Andrew P., and Avril V. Somlyo. Ca2+ Sensitivity of Smooth Muscle and Nonmuscle
Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase. Physiol Rev 83 …

A type III secretion system (TTSS) is encoded on a virulence plasmid that is common to three
pathogenic Yersinia species: Y. enterocolitica, Y. pseudotuberculosis, and Y. pestis …

At steady state, most Rho GTPases are bound in the cytosol to Rho guanine nucleotide
dissociation inhibitors (RhoGDIs). RhoGDIs have generally been considered to hold Rho …

Many bacterial pathogens produce protein toxins to outmanoeuvre the immune system of
the host. Some of these proteins target regulatory GTPases such as those belonging to the …

Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …

A key feature of the virulence of many bacterial pathogens is the ability to deliver effector
proteins into eukaryotic cells via a dedicated type three secretion system (T3SS). Many …

Protein lipidation dramatically affects protein structure, localization, and trafficking via
remodeling protein–membrane and protein–protein interactions through hydrophobic lipid …

Pathogenic Yersinia, including Y. pestis, the agent of plague in humans, and Y.
pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host cells …

Macrophages function at the front line of immune defences against incoming pathogens. But
the ability of macrophages to internalize bacteria, migrate, recruit other immune cells to the …

The type III secretion (T3S) pathway allows bacteria to inject effector proteins into the cytosol
of target animal or plant cells. T3S systems evolved into seven families that were distributed …