The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Stem cell therapy for spinal cord injury

L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

Peripheral nerve injury: stem cell therapy and peripheral nerve transfer

R Sullivan, T Dailey, K Duncan, N Abel… - International journal of …, 2016 - mdpi.com
Peripheral nerve injury can lead to great morbidity in those afflicted, ranging from sensory
loss, motor loss, chronic pain, or a combination of deficits. Over time, research has …

Cell transplantation for spinal cord injury: a systematic review

J Li, G Lepski - BioMed research international, 2013 - Wiley Online Library
Cell transplantation, as a therapeutic intervention for spinal cord injury (SCI), has been
extensively studied by researchers in recent years. A number of different kinds of stem cells …

Design of hydrogel-based scaffolds for the treatment of spinal cord injuries

N Ghane, MH Beigi, S Labbaf… - Journal of Materials …, 2020 - pubs.rsc.org
Spinal cord injury (SCI) is a traumatic lesion that diminishes sensory and/or motor neuronal
functionality, directly affecting the quality of the patient's life. Due to the central nervous …

Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus

H Kanno, DD Pearse, H Ozawa, E Itoi… - Reviews in the …, 2015 - degruyter.com
Abstract Transplantation of Schwann cells (SCs) is a promising therapeutic strategy for
spinal cord repair. The introduction of SCs into the injured spinal cord has been shown to …

A comparative study of three different types of stem cells for treatment of rat spinal cord injury

J Ruzicka, L Machova-Urdzikova, J Gillick… - Cell …, 2017 - journals.sagepub.com
Three different sources of human stem cells—bone marrow-derived mesenchymal stem
cells (BM-MSCs), neural progenitors (NPs) derived from immortalized spinal fetal cell line …

Spinal cord injuries: how could cell therapy help?

A Badner, AM Siddiqui, MG Fehlings - Expert opinion on biological …, 2017 - Taylor & Francis
Introduction: Spinal cord injury (SCI) is a devastating condition, where regenerative failure
and cell loss lead to paralysis. The heterogeneous and time-sensitive pathophysiology has …

Peripheral nerve repair with cultured schwann cells: getting closer to the clinics

MCO Rodrigues, AA Rodrigues Jr… - The Scientific World …, 2012 - Wiley Online Library
Peripheral nerve injuries are a frequent and disabling condition, which affects 13 to 23 per
100.000 persons each year. Severe cases, with structural disruption of the nerve, are …

Biomaterials used in stem cell therapy for spinal cord injury

A Higuchi, SS Kumar, G Benelli, QD Ling, HF Li… - Progress in Materials …, 2019 - Elsevier
Spinal cord injury (SCI) is a common, severe damage to the central nervous system. Here,
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …