Angiotensin II (Ang II) plays a major role in the progression of myocardial hypertrophy to
heart failure. Inhibiting the angiotensin converting enzyme (ACE) or blockade of the …

Thyroid hormones (THs) exert multiple effects on the heart and vascular system. As a
consequence, altered cardiovascular function observed in the thyroid diseases corresponds …

Several studies have implicated the renin angiotensin system in the cardiac hypertrophy
induced by thyroid hormone. However, whether Angiotensin type 1 receptor (AT 1 R) is …

We investigated whether the pathways linked to Toll-like receptors 2 and 4 (TLRs) are
involved in renal ischemia-reperfusion (I/R)-induced cardiac hypertrophy. Wild type (WT) …

The purpose of this study was to investigate the depression-like behavior performances of
subclinical hypothyroidism (SCH) rat. SCH rat model was induced by hemi-thyroid …

Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be
attributed to type 1 Ang II receptor (AT 1 R), the type 2 receptor (AT 2 R) has been shown to …

Corticosteroid control of distal nephron sodium handling, particularly through the amiloride-
sensitive sodium channel (ENaC), has a key role in blood pressure regulation. The …

Background: Iodine is essential for thyroid hormone synthesis and is an important regulator
of thyroid function. Chronic iodine deficiency leads to hypothyroidism, but iodine excess also …

Adequate maternal iodine consumption during pregnancy and lactation guarantees normal
thyroid hormones (TH) production, which is crucial to the development of the fetus. Indeed …

In hypothyroid patients, altered microvascular structure and function may affect mood and
cognitive function. We hypothesized that adult male hypothyroid rats will have significantly …