Targeted liposomal drug delivery: a nanoscience and biophysical perspective

Y Liu, KMC Bravo, J Liu - Nanoscale horizons, 2021 - pubs.rsc.org
Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

Giant vesicles: preparations and applications

P Walde, K Cosentino, H Engel, P Stano - ChemBioChem, 2010 - Wiley Online Library
There is considerable interest in preparing cell‐sized giant unilamellar vesicles from natural
or nonnatural amphiphiles because a giant vesicle membrane resembles the self‐closed …

Membrane curvature and mechanisms of dynamic cell membrane remodelling

HT McMahon, JL Gallop - Nature, 2005 - nature.com
Membrane curvature is no longer seen as a passive consequence of cellular activity but an
active means to create membrane domains and to organize centres for membrane …

Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles

T Baumgart, AT Hammond… - Proceedings of the …, 2007 - National Acad Sciences
The membrane raft hypothesis postulates the existence of lipid bilayer membrane
heterogeneities, or domains, supposed to be important for cellular function, including lateral …

Order of lipid phases in model and plasma membranes

HJ Kaiser, D Lingwood, I Levental… - Proceedings of the …, 2009 - National Acad Sciences
Lipid rafts are nanoscopic assemblies of sphingolipids, cholesterol, and specific membrane
proteins that contribute to lateral heterogeneity in eukaryotic membranes. Separation of …

Nonuniversal impact of cholesterol on membranes mobility, curvature sensing and elasticity

M Pöhnl, MFW Trollmann, RA Böckmann - Nature Communications, 2023 - nature.com
Biological membranes, composed mainly of phospholipids and cholesterol, play a vital role
as cellular barriers. They undergo localized reshaping in response to environmental cues …

Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins

S Suetsugu, S Kurisu, T Takenawa - Physiological reviews, 2014 - journals.physiology.org
All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …

Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes

E Sezgin, I Levantal, G Schwarzmann, V Mueller… - Biophysical …, 2012 - cell.com
296a Monday, February 27, 2012 counterparts remains unknown, especially of lipids such
as sphingolipids that, when unlabeled, enter ''raft''domains in model systems, termed …

Lipid nanotechnology

S Mashaghi, T Jadidi, G Koenderink… - International journal of …, 2013 - mdpi.com
Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices
and machines derived from engineering, physics, materials science, chemistry and biology …