[HTML][HTML] Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019 - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

[HTML][HTML] Modulation of NF-κB signalling by microbial pathogens

MM Rahman, G McFadden - Nature Reviews Microbiology, 2011 - nature.com
The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Gammaherpesviruses and lymphoproliferative disorders

E Cesarman - Annual Review of Pathology: Mechanisms of …, 2014 - annualreviews.org
Epstein–Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV), formally designated
human herpesvirus 4 (HHV-4) and 8 (HHV-8), respectively, are viruses that can cause a …

[HTML][HTML] Independent regulation of renin–angiotensin–aldosterone system in the kidney

A Nishiyama, H Kobori - Clinical and experimental nephrology, 2018 - Springer
Renin–angiotensin–aldosterone system (RAAS) plays important roles in regulating renal
hemodynamics and functions, as well as in the pathophysiology of hypertension and renal …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

KSHV: pathways to tumorigenesis and persistent infection

L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is
the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

Epstein–Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway

T Portis, R Longnecker - Oncogene, 2004 - nature.com
Epstein–Barr virus (EBV) establishes a lifelong latent infection in host B cells and is
associated with the development of a variety of malignancies. The viral LMP2A protein …

Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients

E Cesarman - Cancer letters, 2011 - Elsevier
Two lymphotropic human gamma herpesviruses can cause lymphoproliferative disorders:
Epstein Barr virus (EBV, formally designated as human herpesvirus 4) and Kaposi sarcoma …