Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic Decompensation—Comparing Biological Models and Gaining New Insights into Molecular and …

AR Mathew, G Di Matteo, P La Rosa… - International Journal of …, 2024 - mdpi.com
Vitamin B12 (VitB12) is a micronutrient and acts as a cofactor for fundamental biochemical
reactions: the synthesis of succinyl-CoA from methylmalonyl-CoA and biotin, and the …

Vitamin B12 (Cobalamin) and Micronutrient Fortification in Food Crops Using Nanoparticle Technology

S Oh, G Cave, C Lu - Frontiers in Plant Science, 2021 - frontiersin.org
It is necessary to develop a resilient food supply that will withstand unexpected future shocks
and deliver the required amounts of nutrients to consumers. By increasing the sustainability …

Bioprocess Strategies for Vitamin B12 Production by Microbial Fermentation and Its Market Applications

Á Calvillo, T Pellicer, M Carnicer, A Planas - Bioengineering, 2022 - mdpi.com
Vitamin B12 is a widely used compound in the feed and food, healthcare and medical
industries that can only be produced by fermentation because of the complexity of its …

One-pot synthesis of amphiphilic biopolymers from oxidized alginate and self-assembly as a carrier for sustained release of hydrophobic drugs

Z Liu, X Chen, Z Huang, H Wang, S Cao, C Liu, H Yan… - Polymers, 2022 - mdpi.com
In this paper, we developed an organic solvent-free, eco-friendly, simple and efficient one-
pot approach for the preparation of amphiphilic conjugates (Ugi-OSAOcT) by grafting …

[HTML][HTML] Methotrexate-loaded folic acid of solid-phase synthesis conjugated gold nanoparticles targeted treatment for rheumatoid arthritis

X Li, H Wang, X Zou, H Su, C Li - European Journal of Pharmaceutical …, 2022 - Elsevier
Purpose Methotrexate (MTX) is a first-line drug for rheumatoid arthritis (RA). Targeting of
MTX to inflamed joints is essential to the prevention of potential toxicity and improving …

Pharmacokinetics of vitamin dosage forms: A complete overview

VV Sugandhi, R Pangeni, LK Vora… - Food Science & …, 2024 - Wiley Online Library
Vitamins are crucial for sustaining life because they play an essential role in numerous
physiological processes. Vitamin deficiencies can lead to a wide range of severe health …

Altered vitamin B12 metabolism in the central nervous system is associated with the modification of ribosomal gene expression: new insights from comparative RNA …

AR Mathew, V Cavallucci, M Fidaleo - Functional & Integrative Genomics, 2023 - Springer
Recent studies have confirmed the direct role of vitamin B12 (VitB12) in the central nervous
system (CNS) homeostasis; nevertheless, the detailed mechanisms are poorly understood …

[HTML][HTML] Evaluation of the ameliorative potential of Nutritional Dietary supplementation of vitamin B12 following chronic tramadol hydrochloride exposure induced …

SA Adelakun, B Ogunlade, JA Siyanbade… - Food Chemistry …, 2023 - Elsevier
Vitamin B 12 is an essential water-soluble vitamin, commonly found in a variety of foods. The
present study investigated the effect of Vitamin B 12 on tramadol-induced hepatorenal …

Dietary intake of one-carbon metabolism-related nutrients and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort

T He, H Xiao, M Wusiman, D Yishake, A Fang, Y Luo… - Food & Function, 2022 - pubs.rsc.org
Dietary intake of one-carbon metabolism-related nutrients has been linked to cancer-related
outcomes, but their effects on hepatocellular carcinoma (HCC) mortality are still unknown …

Methylcobalamin as a candidate for chronic peripheral neuropathic pain therapy: review of molecular pharmacology action

A Ramadhani, I Astuti, MG Widiastuti… - The Korean Journal …, 2024 - pmc.ncbi.nlm.nih.gov
Chronic peripheral neuropathic pain therapy currently focuses on modulating
neuroinflammatory conditions. Methylcobalamin (MeCbl), a neuroregenerative agent …