Chronic stress and body composition disorders: implications for health and disease

C Stefanaki, P Pervanidou, D Boschiero, GP Chrousos - Hormones, 2018 - Springer
Recent studies have suggested that body composition is key to health and disease. First, fat
tissue is a complex, essential, and highly active metabolic and endocrine organ that …

Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

Prospect of stem cell therapy and regenerative medicine in osteoporosis

B Arjmand, M Sarvari, S Alavi-Moghadam… - Frontiers in …, 2020 - frontiersin.org
The field of cell therapy and regenerative medicine can hold the promise of restoring normal
tissues structure and function. Additionally, the main targets of stem cell-based therapies are …

Integrative bone metabolomics—lipidomics strategy for pathological mechanism of postmenopausal osteoporosis mouse model

H Zhao, X Li, D Zhang, H Chen, Y Chao, K Wu… - Scientific reports, 2018 - nature.com
Osteoporosis, characterized by bone mass reduction and increased fractures, has become a
global health problem that seriously affects the health of people, especially postmenopausal …

Quercetin protects against iron overload-induced osteoporosis through activating the Nrf2/HO-1 pathway

J Xiao, G Zhang, B Chen, Q He, J Mai, W Chen, Z Pan… - Life Sciences, 2023 - Elsevier
Aims Eucommia is the tree bark of Eucommia japonica, family Eucommiaceae. In traditional
Chinese medicine, Eucommia is often used to treat osteoporosis. Quercetin (QUE), a major …

Discovery of potential biomarkers for osteoporosis using LC-MS/MS metabolomic methods

J Wang, D Yan, A Zhao, X Hou, X Zheng, P Chen… - Osteoporosis …, 2019 - Springer
Our study focused on the associations of metabolites with BMD and osteoporosis, finding
that several metabolites are associated with BMD, and metabolites combined with bone …

Efficient lung-targeted delivery of risedronate sodium/vitamin D3 conjugated PAMAM-G5 dendrimers for managing osteoporosis: Pharmacodynamics, molecular …

NME Elsayyad, I Gomaa, MA Salem, R Amer… - Life sciences, 2022 - Elsevier
Aims This study aims at formulating combined delivery of Risedronate sodium (RIS) and
Vitamin D3 (VITD3) for augmented therapeutic outcome against osteoporosis (OP) using …

Chondroitin sulfate alleviates osteoporosis caused by calcium deficiency by regulating lipid metabolism

T Liu, H Yu, S Wang, H Li, X Du, X He - Nutrition & metabolism, 2023 - Springer
The use of non-drug intervention for calcium deficiency has attracted attention in recent
years. Although calcium carbonate is the preferred raw material for calcium …

Intelligent supramolecular modification for implants: endogenous regulation of bone defect repair in osteoporosis

X Zhou, J Jiang, J Dang, Y Wang, R Hu… - Advanced …, 2024 - Wiley Online Library
Addressing osteoporosis‐related bone defects, a supramolecular strategy is innovated for
modifying carbon fiber reinforced polyether ether ketone (CF/PEEK) composites. By …

Application of metabolomics in osteoporosis research

Z Zhao, Z Cai, A Chen, M Cai, K Yang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoporosis (OP) is a systemic disease characterized by bone metabolism imbalance and
bone microstructure destruction, which causes serious social and economic burden. At …