Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Assessments of sperm DNA damage are controversial because of perceived uncertainties
over the relationship with pregnancy and the limited range of therapies available should …

Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

Spermatogonial stem cells exhibit a low level of spontaneous mutation that is heavily
impacted by paternal age via mechanisms that appear to involve the aberrant repair of DNA …

Preservation of human spermatozoa in vitro at normothermia or hypothermia maintaining
their functions and fertility for several days plays a significant role in reproductive biology …

Cryopreservation may reduce sperm fertility due to cryodamage including physical-chemical
and oxidative stress damages. As a powerful antioxidant, melatonin has been reported to …

Viral infections have haunted humankind since times immemorial. Overpopulation,
globalization, and extensive deforestation have created an ideal environment for a viral …

Melatonin (MT) can improve the effect of cryopreservation on oocytes by suppressing
oxidative stress and maintaining the permeability of the oolemma. In this study, MT was …

Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due
to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction …

Background Suboptimal human semen handling in vitro may induce sperm damage.
However, the effects of semen swim‐up, pellet swim‐up, density gradient, and density …