Nanodrugs with intrinsic radioprotective exertion: Turning the double‐edged sword into a single‐edged knife

J Guo, Z Zhao, ZF Shang, Z Tang, H Zhu, K Zhang - Exploration, 2023 - Wiley Online Library
Ionizing radiation (IR) poses a growing threat to human health, and thus ideal
radioprotectors with high efficacy and low toxicity still receive widespread attention in …

Therapeutic effects of kaempferol affecting autophagy and endoplasmic reticulum stress

M Ashrafizadeh, S Tavakol, Z Ahmadi… - Phytotherapy …, 2020 - Wiley Online Library
Regulated cell death (RCD) guarantees to preserve organismal homeostasis. Apoptosis and
autophagy are two major arms of RCD, while endoplasmic reticulum (ER) as a crucial …

Turmeric and curcumin: from traditional to modern medicine

M Akaberi, A Sahebkar, SA Emami - … on Biomarkers and New Targets in …, 2021 - Springer
The rhizome of turmeric (Curcuma longa L.) has been used as an herbal medicine, coloring
agent, spice, and food additive for thousands of years in different parts of the world …

[HTML][HTML] Complete ablation of tumors using synchronous chemoradiation with bimetallic theranostic nanoparticles

H Nosrati, E Attari, F Abhari, M Barsbay, M Ghaffarlou… - Bioactive Materials, 2022 - Elsevier
Synchronous chemotherapy and radiotherapy, termed chemoradiation therapy, is now an
important standard regime for synergistic cancer treatment. For such treatment …

Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances

Z Yu, C Xu, B Song, S Zhang, C Chen, C Li… - Journal of Translational …, 2023 - Springer
Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …

The multifaced actions of curcumin in pregnancy outcome

G Tossetta, S Fantone, SR Giannubilo, D Marzioni - Antioxidants, 2021 - mdpi.com
Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in
the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been …

Targeting of cancer cell death mechanisms by curcumin: implications to cancer therapy

C Yu, B Yang, M Najafi - Basic & clinical pharmacology & …, 2021 - Wiley Online Library
Cancer is known as a second major cause of death globally. Nowadays, several modalities
have been developed for the treatment of cancer. Radiotherapy and chemotherapy are the …

Radiosensitization and radioprotection by curcumin in glioblastoma and other cancers

V Zoi, V Galani, P Tsekeris, AP Kyritsis, GA Alexiou - Biomedicines, 2022 - mdpi.com
Radiation therapy plays an important role in almost every cancer treatment. However,
radiation toxicity to normal tissues, mainly due to the generation of reactive free radicals, has …

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

K Mortezaee, NH Goradel, P Amini… - Current molecular …, 2019 - ingentaconnect.com
Background: Radiotherapy is a treatment modality for cancer. For better therapeutic
efficiency, it could be used in combination with surgery, chemotherapy or immunotherapy. In …

Cardiac inflammation and fibrosis following chemo/radiation therapy: mechanisms and therapeutic agents

R Yang, C Tan, M Najafi - Inflammopharmacology, 2022 - Springer
The incidence of cardiovascular disorders is one of the most concerns among people who
underwent cancer therapy. The heart side effects of cancer therapy may occur during …