Antiseizure drugs (ASDs), also termed antiepileptic drugs, are the main form of symptomatic
treatment for people with epilepsy, but not all patients become free of seizures. The …

Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

Schizophrenia is a severe, chronic psychiatric disorder that devastates the lives of millions of
people worldwide. The disease is characterized by a constellation of symptoms, ranging …

We report here the discovery and pharmacological characterization of N-(1-benzyl-1 H-
pyrazol-3-yl)-2-phenylacetamide derivatives as potent, selective, brain-penetrating T-type …

Background More than 4 million children are exposed annually to sedatives and general
anaesthetics (GAs) in the USA alone. Recent data suggest that common GAs can be …

Sleep is a vital segment of life, however, the mechanisms of diet promoting sleep are
unclear and are the focus of research. Insomnia is a general sleep disorder and functional …

Sleep EEG spindles have been implicated in attention, sensory processing, synaptic
plasticity and memory consolidation. In humans, deficits in sleep spindles have been …

This review centers on the discoveries made during more than six decades of neuroscience
research on the role of gamma-amino-butyric acid (GABA) as neurotransmitter. In doing so …

A consensus is yet to be reached regarding the exact prevalence of epileptic seizures or
epilepsy in multiple sclerosis (MS). In addition, the underlying pathophysiological basis of …

Childhood absence epilepsy (CAE) is associated with interictal co-morbid symptoms
including abnormalities in social behaviour. Genetic Absence Epilepsy Rats from Strasbourg …