Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis

SO Tone, V Kocaba, M Böhm, A Wylegala… - Progress in Retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Heritability of glaucoma and glaucoma-related endophenotypes: Systematic review and meta-analysis

NG Asefa, A Neustaeter, NM Jansonius… - Survey of ophthalmology, 2019 - Elsevier
We have systematically extracted all available heritability (h 2) estimates of glaucoma and
related endophenotypes from the literature and summarized the evidence by meta-analysis …

Determining subclinical edema in Fuchs endothelial corneal dystrophy: revised classification using Scheimpflug tomography for preoperative assessment

SY Sun, K Wacker, KH Baratz, SV Patel - Ophthalmology, 2019 - Elsevier
Purpose To determine if Scheimpflug tomography can identify subclinical corneal edema in
Fuchs endothelial corneal dystrophy (FECD), and to recommend a new classification of …

[HTML][HTML] Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

CY Cheng, M Schache, MK Ikram, TL Young… - The American Journal of …, 2013 - cell.com
Refractive errors are common eye disorders of public health importance worldwide. Ocular
axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia …

[HTML][HTML] Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

NA Afshari, RP Igo Jr, NJ Morris, D Stambolian… - Nature …, 2017 - nature.com
The structure of the cornea is vital to its transparency, and dystrophies that disrupt corneal
organization are highly heritable. To understand the genetic aetiology of Fuchs endothelial …

Corneal high-order aberrations and backscatter in Fuchs' endothelial corneal dystrophy

K Wacker, JW McLaren, SR Amin, KH Baratz, SV Patel - Ophthalmology, 2015 - Elsevier
Purpose Suboptimal visual acuity after endothelial keratoplasty has been attributed to
increased anterior corneal high-order aberrations (HOAs). In this study, we determined …

Fuchs' endothelial corneal dystrophy: subjective grading versus objective grading based on the central-to-peripheral thickness ratio

DJ Repp, DO Hodge, KH Baratz, JW McLaren, SV Patel - Ophthalmology, 2013 - Elsevier
PURPOSE: To assess interobserver agreement between 2 corneal specialists grading
Fuchs' dystrophy clinically and to determine if the corneal central-to-peripheral thickness …

Predicting the prognosis of Fuchs endothelial corneal dystrophy by using Scheimpflug tomography

SV Patel, DO Hodge, EJ Treichel, MR Spiegel… - Ophthalmology, 2020 - Elsevier
Purpose To determine if Scheimpflug tomography pachymetry map and posterior elevation
map patterns, central corneal thickness (CCT), and corneal backscatter can predict the …

Relationship of Fuchs endothelial corneal dystrophy severity to central corneal thickness

LJ Kopplin, K Przepyszny, B Schmotzer… - Archives of …, 2012 - jamanetwork.com
Objective To define the relationship between Fuchs endothelial corneal dystrophy (FECD)
severity and central corneal thickness (CCT). Methods We examined 1610 eyes from a …