Transcription factors in liver development, differentiation, and regeneration

RH Costa, VV Kalinichenko, AXL Holterman… - Hepatology, 2003 - journals.lww.com
Transcriptional Activation. The liver performs essential functions in the body by uniquely
expressing hepatocyte-specific genes encoding plasma proteins, clotting factors and …

Transcription factors in mouse lung development and function

RH Costa, VV Kalinichenko… - American Journal of …, 2001 - journals.physiology.org
Development of the mouse lung initiates on day 9.5 postcoitum from the laryngotracheal
groove and involves mesenchymal-epithelial interactions, in particular, those between the …

All About Albumin: Biochemistry, Genetics, and Medical Applications. Theodore Peters, Jr. San Diego, CA: Academic Press, 1996, 432 pp, $85.00. ISBN 0-12-552110 …

E Azzazy, RH Christenson - 1997 - academic.oup.com
Albumin, the most abundant plasma protein, is among the most studied of all proteins, being
important from clinical monitoring, physiological, and therapeutic perspectives. This unique …

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

C Pigeon, G Ilyin, B Courselaud, P Leroyer… - Journal of biological …, 2001 - ASBMB
Considering that the development of hepatic lesions related to iron overload diseases might
be a result of abnormally expressed hepatic genes, we searched for new genes up …

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

DE Zhang, P Zhang, N Wang… - Proceedings of the …, 1997 - National Acad Sciences
Transcription factors are master regulatory switches of differentiation, including the
development of specific hematopoietic lineages from stem cells. Here we show that mice …

A nuclear factor for IL‐6 expression (NF‐IL6) is a member of a C/EBP family.

S Akira, H Isshiki, T Sugita, O Tanabe… - The EMBO …, 1990 - embopress.org
NF‐IL6 is a nuclear factor that specifically binds to an IL1‐responsive element in the IL‐6
gene. In this study the gene encoding NF‐IL6 has been cloned by direct screening of a …

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

WC Yeh, Z Cao, M Classon… - Genes & …, 1995 - genesdev.cshlp.org
Terminal differentiation of cultured 3T3-L1 fibroblasts to the adipogenic phenotype is
potently stimulated by dexamethasone (DEX) and methylisobutylxanthine (MIX). Previous …

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

FM Sladek, WM Zhong, E Lai… - Genes & …, 1990 - genesdev.cshlp.org
Abstract HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds
to sites required for the transcription of the genes for transthyretin (TTR), the carrier protein in …

CCAAT/enhancer binding protein α is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

HS Radomska, CS Huettner, PU Zhang… - … and cellular biology, 1998 - Taylor & Francis
The transcription factor CCAAT/enhancer binding protein α (C/EBPα) regulates a number of
myeloid cell-specific genes. To delineate the role of C/EBPα in human granulopoiesis, we …

Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells.

SO Freytag, DL Paielli, JD Gilbert - Genes & development, 1994 - genesdev.cshlp.org
The CCAAT/enhancer-binding protein alpha (C/EBP alpha) has been implicated in the
regulation of adipoblast differentiation. In this study we investigate the potential of C/EBP …