[HTML][HTML] IPM-Biological and integrated management of desert locust
Locusts have caused periodic disasters in the recorded history of humankind. Up to now,
locust disaster is still the biggest threat to the world's agricultural production. The desert …
locust disaster is still the biggest threat to the world's agricultural production. The desert …
Insights into the venom composition of the ectoparasitoid wasp Nasonia vitripennis from bioinformatic and proteomic studies
DC De Graaf, M Aerts, M Brunain… - Insect molecular …, 2010 - Wiley Online Library
With the Nasonia vitripennis genome sequences available, we attempted to determine the
proteins present in venom by two different approaches. First, we searched for the transcripts …
proteins present in venom by two different approaches. First, we searched for the transcripts …
Pacifastin-related peptides: structural and functional characteristics of a family of serine peptidase inhibitors
B Breugelmans, G Simonet, V van Hoef, S Van Soest… - Peptides, 2009 - Elsevier
Members of the pacifastin family are serine peptidase inhibitors, found in arthropods and
have many members within different insect orders. Based on their structural characteristics …
have many members within different insect orders. Based on their structural characteristics …
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and-2 are essential for lectin pathway activation and reveal …
The lectin pathway is an antibody-independent activation route of the complement system. It
provides immediate defense against pathogens and altered self-cells, but it also causes …
provides immediate defense against pathogens and altered self-cells, but it also causes …
Structure and stability of β‐pleated sheets
Beside α‐helices, β‐sheets are the most common secondary structure elements of proteins.
In this article, the question of structure and stability of parallel and antiparallel sheets of …
In this article, the question of structure and stability of parallel and antiparallel sheets of …
Enzyme: substrate hydrogen bond shortening during the acylation phase of serine protease catalysis
Atomic resolution (≤ 1.2 Å) serine protease intermediate structures revealed that the
strength of the hydrogen bonds between the enzyme and the substrate changed during …
strength of the hydrogen bonds between the enzyme and the substrate changed during …
Extended intermolecular interactions in a serine protease–canonical inhibitor complex account for strong and highly specific inhibition
We have previously shown that a trypsin inhibitor from desert locust Schistocerca gregaria
(SGTI) is a taxon-specific inhibitor that inhibits arthropod trypsins, such as crayfish trypsin …
(SGTI) is a taxon-specific inhibitor that inhibits arthropod trypsins, such as crayfish trypsin …
High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4′ acidic residues
Human chymotrypsin C (CTRC) is a pancreatic protease that participates in the regulation of
intestinal digestive enzyme activity. Other chymotrypsins and elastases are inactive on the …
intestinal digestive enzyme activity. Other chymotrypsins and elastases are inactive on the …
Directed evolution of canonical loops and their swapping between unrelated serine proteinase inhibitors disprove the interscaffolding additivity model
Reversible serine proteinase inhibitors comprise 18 unrelated families. Each family has a
distinct representative structure but contains a surface loop that adopts the same, canonical …
distinct representative structure but contains a surface loop that adopts the same, canonical …
A review of the most important classes of serine protease inhibitors in insects and leeches
The constant increase of life expectancy is associated with major aging of developed
populations. This indicates that the new century will have one of most epidemic …
populations. This indicates that the new century will have one of most epidemic …