Robust optimization strategies for contour uncertainties in online adaptive radiation therapy
A Smolders, I Bengtsson, A Forsgren… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Online adaptive radiation therapy requires fast and automated contouring of daily
scans for treatment plan re-optimization. However, automated contouring is imperfect and …
scans for treatment plan re-optimization. However, automated contouring is imperfect and …
Implications of using the clinical target distribution as voxel-weights in radiation therapy optimization
I Bengtsson, A Forsgren… - Physics in Medicine & …, 2023 - iopscience.iop.org
Objective. Delineating and planning with respect to regions suspected to contain
microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently …
microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently …
Exploring trade‐offs in treatment planning for brain tumor cases with a probabilistic definition of the clinical target volume
Purpose This study demonstrates how a novel probabilistic clinical target volume (CTV)
concept—the clinical target distribution (CTD)—can be used to navigate the trade‐off …
concept—the clinical target distribution (CTD)—can be used to navigate the trade‐off …
[PDF][PDF] Exploring the Computational and Clinical Added-value of Probabilistic Optimization in Proton Therapy
E Peeters, R Schyns, JA Lee, E Sterpin - dial.uclouvain.be
The definition of the clinical target volume can be considered as a binary mask. However,
the further a point is from the gross target volume, the less probability it has of being …
the further a point is from the gross target volume, the less probability it has of being …
[PDF][PDF] Robust treatment planning for proton therapy
G Buti - dial.uclouvain.be
The dose concentration at the proton end-of-range has the potential to significantly reduce
radiation exposure to healthy tissues while maintaining the curative dose to the tumor …
radiation exposure to healthy tissues while maintaining the curative dose to the tumor …
[PDF][PDF] Implementation of probabilistic robust optimization with contour propagation uncertainty in adaptive radiotherapy
C Gaban, E Sterpin - dial.uclouvain.be
Background: Radiotherapy aims to effectively target tumor volumes with adequate doses
while preserving nearby healthy cells. It is challenged by the dynamic nature of patient …
while preserving nearby healthy cells. It is challenged by the dynamic nature of patient …