Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells
M Grzonka, H Bazzi - Elife, 2024 - elifesciences.org
Abstract SAS-6 (SASS6) is essential for centriole formation in human cells and other
organisms but its functions in the mouse are unclear. Here, we report that Sass6-mutant …
organisms but its functions in the mouse are unclear. Here, we report that Sass6-mutant …
Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold
N Morellet, P Hardouin, N Assrir, C van Heijenoort… - Biomolecules, 2022 - mdpi.com
RNase Y is a crucial component of genetic translation, acting as the key enzyme initiating
mRNA decay in many Gram-positive bacteria. The N-terminal domain of Bacillus subtilis …
mRNA decay in many Gram-positive bacteria. The N-terminal domain of Bacillus subtilis …
Case report: prenatal recurrent microcephaly and corpus callosum abnormalities in a Chinese family with novel biallelic SASS6 mutations
Introduction: Primary microcephaly (MCPH) is not an uncommon disorder with multiple
etiologies. There are a growing number of MCPH-related genes discovered due to the …
etiologies. There are a growing number of MCPH-related genes discovered due to the …
A Sarcocystidae-Specific striated fiber assemblin protein SFA5 is required for parasite division in Toxoplasma gondii
Y Li, X Tang, K He, H Dong, HY Ding, XT Wu… - One Health …, 2024 - Springer
Apicomplexan encompass a variety of intracellular parasites responsible for significant
diseases in humans and animals, such as malaria and toxoplasmosis. Among these …
diseases in humans and animals, such as malaria and toxoplasmosis. Among these …
Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance
L Agostini, J Pfister, N Basnet, J Ding, R Zhang… - bioRxiv, 2024 - biorxiv.org
SSNA-1 is a fibrillar protein localized at the area where dynamic microtubule remodeling
occurs including centrosomes. Despite the important activities of SSNA1 to microtubules …
occurs including centrosomes. Despite the important activities of SSNA1 to microtubules …
Cartwheels create symmetry and asymmetry
T Ochi - Structure, 2022 - cell.com
In this issue of Structure, Kantsadi et al.(2022) present the crystal structures of coiled-coil
bundles from SAS-6, a core component of the centriole cartwheel, and reveal that two coiled …
bundles from SAS-6, a core component of the centriole cartwheel, and reveal that two coiled …