Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

In genetic engineering, the revolutionary CRISPR-Cas system has proven to be a vital tool
for precise genome editing. Simultaneously, the emergence and rapid evolution of deep …

The clinical diagnosis of pathogen infectious diseases increasingly requires sensitive and
rapid RNA detection technologies. The RNA-guided clustered regularly interspaced short …

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
(Cas) proteins are an innovative tool in molecular diagnostics owing to their high specificity …

DNA walkers, an artificial dynamic DNA nanomachine, can mimic actin to move rapidly
along a predefined nucleic acid track. They can generally be classified one-(1D), two-(2D) …

Rapid, accurate, and noninvasive detection of biomarkers in saliva, urine, or nasal fluid is
essential for the identification, early diagnosis, and monitoring of cancer, organ failure …

Small extracellular–vesicule-associated microRNA (sEV-miRNA) is an important biomarker
for cancer diagnosis. However, rapid and sensitive detection of low-abundance sEV-miRNA …

Rapid, accurate, and portable on-site detection is critical in the face of public health
emergencies. Infectious disease control and public health emergency policymaking can …

Exosomes are seen as promising biomarkers for minimally invasive liquid biopsies and
disease surveillance. However, the complexity of body fluids, inherent heterogeneity, and …

Freshwater lead pollution has posed severe threat to the environment and human health,
underscoring the urgent necessity for accurate and user-friendly detection methods. Herein …