Motor output results from the coordinated activity of neural circuits distributed across multiple
brain regions that convey information to the spinal cord via descending motor pathways. Yet …

Neuropathic pain is a significant and persistent issue for individuals with spinal cord injuries
(SCI), severely impacting their quality of life. While changes at the peripheral and spinal …

The spinal cord receives inputs from the cortex via corticospinal neurons (CSNs). While
predominantly a contralateral projection, a less-investigated minority of its axons terminate …

It remains unclear how classical models of motor cortical hierarchy align with emerging
evidence of behavioral organization in motor cortex. To address this, we combined …

Descending corticospinal tract (CST) connections to the neurons of the cervical spinal cord
are vital for performance of forelimb-specific fine motor skills. In rodents, CST axons are …

Corticospinal neurons (CSNs) are located in the cortex and projecting into the spinal cord.
The activation of CSNs, which is associated with skilled motor behaviors, induces the …

Chronic neuropathic pain is a persistent and debilitating outcome of traumatic central
nervous system injury, affecting up to 80% of individuals with chronic injury. Post-injury pain …

There are currently approximately 300,000 individuals living with a spinal cord injury (SCI) in
the United States with an additional 17,000 injuries occurring each year. Perhaps of equal …

Longtemps, les neurobiologistes ont seulement pu placer les indices des diverses activités
cérébrales sur des cartes anatomiques du cerveau dont la résolution atteignait tout juste …