Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

Epithelial ovarian cancer is typically diagnosed at an advanced stage. Current state-of-the-
art surgery and chemotherapy result in the high incidence of complete remissions; however …

Ovarian cancer is one of the leading causes of death in patients with gynecological
malignancy. Despite optimal cytoreductive surgery and platinum-based chemotherapy …

Ovarian cancer (OC) remains a fatal malignancy because most patients experience
recurrent disease, which is resistant to chemotherapy. The outcomes for patients with …

Advanced and recurrent gynecological cancers are associated with poor prognosis and lack
of effective treatment. The developments of the molecular mechanisms on cancer …

Ovarian cancer is the leading cause of gynecological cancer-related mortality globally. The
majority of ovarian cancer patients suffer from relapse after standard of care therapies and …

Highlights•Platinum-based chemotherapy remains the most active treatment for ovarian
cancer.•Platinum should not be withheld after response to last platinum and a treatment-free …

Background Anti-angiogenic therapy combined with chemotherapy could improve the
outcomes of patients with platinum-resistant ovarian cancer. Apatinib is an oral tyrosine …

Ovarian cancer remains the most mortal gynecological cancer in the world. The standard
treatment for ovarian cancer remains cytoreductive surgery followed by platinum-based …

Several data support a central role for angiogenesis in breast cancer growth and metastasis.
Observational studies have demonstrated that microvascular density (MVD) is a prognostic …