[HTML][HTML] Brain-derived estrogen and neural function

DW Brann, Y Lu, J Wang, Q Zhang, R Thakkar… - Neuroscience & …, 2022 - Elsevier
Although classically known as an endocrine signal produced by the ovary, 17β-estradiol (E
2) is also a neurosteroid produced in neurons and astrocytes in the brain of many different …

A neural circuit perspective on brain aromatase

JA Spool, JF Bergan, L Remage-Healey - Frontiers in neuroendocrinology, 2022 - Elsevier
This review explores the role of aromatase in the brain as illuminated by a set of conserved
network-level connections identified in several vertebrate taxa. Aromatase-expressing …

Membrane-initiated actions of sex steroids and reproductive behavior: A historical account

J Balthazart - Molecular and Cellular Endocrinology, 2021 - Elsevier
It was assumed for a long time that sex steroids are activating reproductive behaviors by the
same mechanisms that produce their morphological and physiological effects in the …

The form, function, and evolutionary significance of neural aromatization

BA Schlinger, L Remage-Healey… - Frontiers in …, 2022 - Elsevier
Songbirds have emerged as exceptional research subjects for helping us appreciate and
understand estrogen synthesis and function in brain. In the context of recognizing the …

Estrogen as a neuroprotectant in both sexes: stories from the bird brain

CJ Saldanha - Frontiers in Neurology, 2020 - frontiersin.org
Estrogens such as estradiol (E2) are potent effectors of neural structure and function via
peripheral and central synthesis. In the zebra finch (Taeniopygia guttata), neural E2 …

Estrogens rapidly shape synaptic and intrinsic properties to regulate the temporal precision of songbird auditory neurons

GB Scarpa, JR Starrett, GL Li, C Brooks… - Cerebral …, 2023 - academic.oup.com
Sensory neurons parse millisecond-variant sound streams like birdsong and speech with
exquisite precision. The auditory pallial cortex of vocal learners like humans and songbirds …

Analogies of human speech and bird song: From vocal learning behavior to its neural basis

Y Zhang, L Zhou, J Zuo, S Wang, W Meng - Frontiers in Psychology, 2023 - frontiersin.org
Vocal learning is a complex acquired social behavior that has been found only in very few
animals. The process of animal vocal learning requires the participation of sensorimotor …

Neurobiology of Social Interactions Across Species Role of neuroestrogens in the regulation of social behaviors–From social recognition to mating

D Aspesi, CA Cornil - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
In this mini-review, we summarize the brain distribution of aromatase, the enzyme catalyzing
the synthesis of estrogens from androgens, and the mechanisms responsible for regulating …

Auditory pallial regulation of the social behavior network

JA Spool, AP Lally, L Remage-Healey - Communications Biology, 2024 - nature.com
Sensory cues such as vocalizations contain important social information. Processing social
features of vocalizations (eg, vocalizer identity, emotional state) necessitates unpacking the …

Lesions to Caudomedial Nidopallium Impair Individual Vocal Recognition in the Zebra Finch

K Yu, WE Wood, LG Johnston… - Journal of …, 2023 - Soc Neuroscience
Many social animals can recognize other individuals by their vocalizations. This requires a
memory system capable of mapping incoming acoustic signals to one of many known …