[HTML][HTML] Research progress of natural product-based nanomaterials for the treatment of inflammation-related diseases

F Cao, SY Gui, X Gao, W Zhang, ZY Fu, LM Tao… - Materials & Design, 2022 - Elsevier
Inflammatory diseases present with dysregulated inflammatory reactions and oxidative
stress, resulting in heavy health-associated economic burden to society. Current mainstream …

Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment

H Li, R Gou, J Liao, Y Wang, R Qu, Q Tang… - Acta Materia …, 2023 - scienceopen.com
Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage
destruction and periarticular bone erosion, thus ultimately compromising joint integrity and …

Chitosan-based biomaterials for the treatment of bone disorders

M Rahimi, SM Mir, R Baghban, G Charmi… - International Journal of …, 2022 - Elsevier
Bone is an alive and dynamic organ that is well-differentiated and originated from
mesenchymal tissues. Bone undergoes continuous remodeling during the lifetime of an …

Development of an intelligent, stimuli-responsive transdermal system for efficient delivery of Ibuprofen against rheumatoid arthritis

D Khan, M Qindeel, N Ahmed, MI Asad… - International Journal of …, 2021 - Elsevier
The present study aimed to fabricate and evaluate the therapeutic efficacy of pH-responsive
Ibuprofen (IB) nanoparticles (NPs) loaded transdermal hydrogel against rheumatoid arthritis …

Metals-triggered compound CDPDP exhibits anti-arthritic behavior by downregulating the inflammatory cytokines, and modulating the oxidative storm in mice models …

SS Hassan, SQ Abbas, I Muhammad, JJ Wu… - Frontiers in …, 2022 - frontiersin.org
Triggering through abiotic stress, including chemical triggers like heavy metals, is a new
technique for drug discovery. In this research, the effect of heavy metal Nickel on …

Lipase-sensitive fusidic acid polymeric nanoparticles based hydrogel for on-demand delivery against MRSA-infected burn wounds

N Ullah, D Khan, N Ahmed, A Zafar, KU Shah… - Journal of Drug Delivery …, 2023 - Elsevier
The present study aimed to develop lipase-sensitive nanoparticles-based hydrogel for
topical delivery of fusidic acid (FA) against wound infection. Lipase sensitive nanosystem for …

Phytonanomedicines, a state-of-the-art strategy for targeted delivery of anti-inflammatory phytochemicals: a review of improved pharmacokinetic profile and …

Z Hussain, HE Thu, S Khan, M Sohail… - Journal of Drug Delivery …, 2022 - Elsevier
Owing to their eco-friendliness, natural abundance, cost-effectiveness, and organic nature,
numerous phytochemicals are being traditionally used for treatment of different diseases …

PLGA/PCADK composite microspheres containing hyaluronic acid–chitosan SiRNA nanoparticles: A rational design for rheumatoid arthritis therapy

M Zhao, T Zhu, J Chen, Y Cui, X Zhang, RJ Lee… - International Journal of …, 2021 - Elsevier
Abstract Myeloid cell leukemia-1 (Mcl-1), a member of the Bcl-2 anti-apoptotic family, is
overexpressed in the synovial macrophages of patients with rheumatoid arthritis (RA). Small …

Embelin: A novel XIAP inhibitor for the prevention and treatment of chronic diseases

U Devi Daimary, S Girisa, D Parama… - … of Biochemical and …, 2022 - Wiley Online Library
Chronic diseases are a serious health concern worldwide, especially in the elderly
population. Most chronic diseases like cancer, cardiovascular ailments, neurodegenerative …

Simulation-Based Research on Phytoconstituents of Embelia ribes Targeting Proteins with Pathophysiological Implications in Rheumatoid Arthritis

AF Radu, PA Negru, A Radu, AG Tarce, SG Bungau… - Life, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a heterogeneous inflammatory disease with an autoimmune
origin and an incompletely elucidated pathophysiological mechanism. RA pharmacotherapy …