A Michelucci, C Liang, F Protasi, RT Dirksen - Metabolites, 2021 - mdpi.com
Skeletal muscle contraction relies on both high-fidelity calcium (Ca2+) signals and robust capacity for adenosine triphosphate (ATP) generation. Ca2+ release units (CRUs) are highly …
P Bolaños, JC Calderón - Frontiers in Physiology, 2022 - frontiersin.org
The excitation–contraction coupling (ECC) in skeletal muscle refers to the Ca2+-mediated link between the membrane excitation and the mechanical contraction. The initiation and …
S Boncompagni, C Pecorai, A Michelucci… - Frontiers in …, 2021 - frontiersin.org
Tubular aggregates (TAs) in skeletal muscle fibers are unusual accumulation of sarcoplasmic reticulum (SR) tubes that are found in different disorders including TA …
F Protasi, L Pietrangelo, S Boncompagni - Journal of Muscle Research …, 2021 - Springer
In the last decades the term Store-operated Ca 2+ entry (SOCE) has been used in the scientific literature to describe an ubiquitous cellular mechanism that allows recovery of …
A Michelucci, S Boncompagni, L Pietrangelo… - Journal of General …, 2020 - rupress.org
Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ influx mechanism triggered by depletion of Ca2+ stores from the endoplasmic/sarcoplasmic reticulum (ER/SR). We recently …
F Protasi, B Girolami, S Roccabianca… - Current Opinion in …, 2023 - Elsevier
Abstract Store-Operated Ca 2+ entry (SOCE) is recognized as a key mechanism in muscle physiology necessary to refill intracellular Ca 2+ stores during sustained muscle activity. For …
Calsequestrin (CASQ) is the most abundant Ca 2+ binding protein localized in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. The genome of vertebrates …
M García-Castañeda, A Michelucci, N Zhao… - Journal of General …, 2022 - rupress.org
Duchenne muscular dystrophy (DMD), an X-linked disorder caused by loss-of-function mutations in the dystrophin gene, is characterized by progressive muscle degeneration and …