Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Monomolecular arrays of protein or glycoprotein subunits forming surface layers (S-layers)
are one of the most commonly observed prokaryotic cell envelope components. S-layers are …

The outer surface of many archaea and bacteria is coated with a proteinaceous surface
layer (known as an S-layer), which is formed by the self-assembly of monomeric proteins …

Bacteria within biofilms are protected from multiple stresses, including immune responses
and antimicrobial agents. The biofilm-forming ability of bacterial pathogens has been …

Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

Clostridium difficile causes antibiotic-associated diarrhea and pseudomembranous colitis by
production of the Rho GTPase-glucosylating toxins A and B. Recently emerging …

The worldwide emergence of epidemic strains of Clostridium difficile linked to increased
disease severity and mortality has resulted in greater research efforts toward determining …

Clostridium difficile infection is the leading cause of antibiotic-and healthcare-associated
diarrhea, and its containment and treatment imposes a significant financial burden …

Protein translocation across the cytoplasmic membrane is an essential process in all
bacteria. The Sec system, comprising at its core an ATPase, SecA, and a membrane …

Clostridium difficile is the prominent etiological agent of healthcare-associated diarrhea. The
disease symptoms range from mild diarrhea to life-threatening pseudomembranous colitis …