NAD+ Homeostasis and NAD+-Consuming Enzymes: Implications for Vascular Health

R Campagna, A Vignini - Antioxidants, 2023 - mdpi.com
Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in
many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been …

Advancements in NMN biotherapy and research updates in the field of digestive system diseases

G Liao, Y Xie, H Peng, T Li, X Zou, F Yue, J Guo… - Journal of Translational …, 2024 - Springer
Nicotinamide mononucleotide (NMN), a crucial intermediate in NAD+ synthesis, can rapidly
transform into NAD+ within the body after ingestion. NMN plays a pivotal role in several …

Systematic Engineering of Escherichia coli for Efficient Production of Nicotinamide Mononucleotide From Nicotinamide

Z Huang, N Li, S Yu, W Zhang, T Zhang… - ACS Synthetic …, 2022 - ACS Publications
Research studies on NAD+ have proven its crucial role in aging and disease. Nicotinamide
mononucleotide (NMN), as the key intermediate of NAD+, plays a significant role in …

Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women

Y Fukamizu, Y Uchida, A Shigekawa, T Sato… - Scientific reports, 2022 - nature.com
A decrease in the intracellular level of nicotinamide adenine dinucleotide (NAD+), an
essential coenzyme for metabolic activity, causes various age-related diseases and …

The acute effect of different NAD+ precursors included in the combined metabolic activators

X Li, H Yang, H Jin, H Turkez, G Ozturk… - Free Radical Biology …, 2023 - Elsevier
NAD+ and glutathione precursors are currently used as metabolic modulators for improving
the metabolic conditions associated with various human diseases, including non-alcoholic …

The impacts of short-term NMN supplementation on serum metabolism, fecal microbiota, and telomere length in pre-aging phase

KM Niu, T Bao, L Gao, M Ru, Y Li, L Jiang, C Ye… - Frontiers in …, 2021 - frontiersin.org
Aging is a natural process with concomitant changes in the gut microbiota and associate
metabolomes. Beta-nicotinamide mononucleotide, an important NAD+ intermediate, has …

Nad+ precursors nicotinamide mononucleotide (nmn) and nicotinamide riboside (nr): Potential dietary contribution to health

GFS Alegre, GM Pastore - Current nutrition reports, 2023 - Springer
Purpose of Review NAD+ is a vital molecule that takes part as a redox cofactor in several
metabolic reactions besides being used as a substrate in important cellular signaling in …

NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

HG Lee, NK Hong, YT Chang - Chemical Communications, 2023 - pubs.rsc.org
The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid.
NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence …

Maternal obesity and offspring health: Adapting metabolic changes through autophagy and mitophagy

L Wang, AM O'Kane, Y Zhang, J Ren - Obesity Reviews, 2023 - Wiley Online Library
Maternal obesity leads to obstetric complications and a high prevalence of metabolic
anomalies in the offspring. Among various contributing factors for maternal obesity‐evoked …

Effects of β-nicotinamide mononucleotide, berberine, and cordycepin on lipid droplet content and developmental ability of vitrified bovine oocytes

X Xu, B Yang, H Zhang, X Feng, H Hao, W Du, H Zhu… - Antioxidants, 2023 - mdpi.com
Oocyte vitrification is crucial for livestock reproduction, germplasm conservation, and human-
assisted reproduction, but the overabundance of lipids is highly detrimental to oocyte …