Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

[HTML][HTML] Pseudomonas aeruginosa biofilms and their partners in crime

M del Mar Cendra, E Torrents - Biotechnology advances, 2021 - Elsevier
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact
with a broad range of microorganisms have a substantial clinical impact. This review focuses …

A genetic switch controls Pseudomonas aeruginosa surface colonization

C Manner, R Dias Teixeira, D Saha… - Nature …, 2023 - nature.com
Efficient colonization of mucosal surfaces is essential for opportunistic pathogens like
Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize …

Pseudomonas Flagella: Generalities and Specificities

M Bouteiller, C Dupont, Y Bourigault, X Latour… - International journal of …, 2021 - mdpi.com
Flagella-driven motility is an important trait for bacterial colonization and virulence. Flagella
rotate and propel bacteria in liquid or semi-liquid media to ensure such bacterial fitness …

Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence

E Razvi, GB Whitfield, C Reichhardt… - npj Biofilms and …, 2023 - nature.com
Pel exopolysaccharide biosynthetic loci are phylogenetically widespread biofilm matrix
determinants in bacteria. In Pseudomonas aeruginosa, Pel is crucial for cell-to-cell …

Bacterial cyclic diguanylate signaling networks sense temperature

H Almblad, TE Randall, F Liu, K Leblanc… - Nature …, 2021 - nature.com
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility,
biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase …

From genotype to phenotype: adaptations of Pseudomonas aeruginosa to the cystic fibrosis environment

L Camus, F Vandenesch, K Moreau - Microbial genomics, 2021 - microbiologyresearch.org
Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Sensory perception in bacterial cyclic diguanylate signal transduction

TE Randall, K Eckartt, S Kakumanu… - Journal of …, 2022 - Am Soc Microbiol
Cyclic diguanylate (c-di-GMP) signal transduction systems provide bacteria with the ability to
sense changing cell status or environmental conditions and then execute suitable …

Adaptation and genomic erosion in fragmented Pseudomonas aeruginosa populations in the sinuses of people with cystic fibrosis

CR Armbruster, CW Marshall, AI Garber, JA Melvin… - Cell reports, 2021 - cell.com
Pseudomonas aeruginosa notoriously adapts to the airways of people with cystic fibrosis
(CF), yet how infection-site biogeography and associated evolutionary processes vary as …

An inside look at a biofilm: Pseudomonas aeruginosa flagella biotracking

E Ozer, K Yaniv, E Chetrit, A Boyarski, MM Meijler… - Science …, 2021 - science.org
The opportunistic pathogen, Pseudomonas aeruginosa, a flagellated bacterium, is one of
the top model organisms for biofilm studies. To elucidate the location of bacterial flagella …