OBJECTIVES: Recent literature has highlighted histological types of ovarian carcinoma as
distinct diseases, each with unique clinical and molecular features. Historically, the …

OBJECTIVE: Different histologic types of epithelial ovarian cancer may represent different
diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of …

The ERBB or EGF receptor (EGFR) proto-oncogene family, which consists of four structurally-
related transmembrane receptors (ie, EGFR, ErbB2, ErbB3, and ErbB4), plays an etiological …

The ultimate goal of defining cancer specific precursors is to facilitate early detection and
intervention before the development of invasive malignancy. Unlike other malignancies …

Ovarian clear cell carcinoma (OCCC) shows unique clinical features including an
association with endometriosis and poor prognosis. We previously reported that the contents …

Epithelial ovarian cancer, which comprises several histologic types and grades, is the most
lethal cancer among women in the United States. In this review, we summarize recent …

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …

Objective Ovarian clear cell carcinomas (OCCCs) are rare, and uncertainty exists as to the
optimal treatment paradigm and validity of the FIGO staging system, especially in early-stage …

Transitional cell tumors of the ovary include 2 distinct clinicopathologic categories: Brenner
tumors and transitional cell carcinomas (TCCs). Their molecular genetic alterations have not …

Ovarian clear cell adenocarcinomas (OCCAs) account for< 5% of all ovarian malignancies.
Compared to other epithelial ovarian cancer (EOC) subtypes, when at an advanced stage …