Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

Angiogenesis is the formation of new capillaries from pre-existing vasculature, which plays a
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …

The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory
responses both in response to and acting as danger signals. It has long been established …

Angiogenesis, the growth of new blood vessels, is essential in the pathogenesis of joint
inflammatory disorders such as rheumatoid arthritis (RA) and osteoarthritis (OA), facilitating …

Inflammasomes are intracellular multiprotein signaling platforms that initiate inflammatory
responses in response to pathogens and cellular damage. Active inflammasomes induce …

Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …

Simple Summary Tumor angiogenesis is one of the most critical steps in the progression of
cancer. Owing to its fundamental role in tumor growth and metastasis, tumor angiogenesis is …

Diabetic wounds, one of the most enervating complications of diabetes mellitus, affect
millions of people worldwide annually. Vascular insufficiency, caused by hyperglycemia, is …

Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous
manifestations including severe organ damage and vascular dysfunction leading to …

Interleukin-18 (IL-18) is a highly regulated inflammatory cytokine that is elevated in synovial
tissues and synovial fluids of patients with rheumatoid arthritis (RA) compared with patients …