Potential applications of nanomaterials and technology for diabetic wound healing

Q Bai, K Han, K Dong, C Zheng, Y Zhang… - International journal …, 2020 - Taylor & Francis
Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Biological macromolecules-based nanoformulation in improving wound healing and bacterial biofilm-associated infection: A review

SS Garg, R Dubey, S Sharma, A Vyas… - International Journal of …, 2023 - Elsevier
A chronic wound is a serious complication associated with diabetes mellitus and is difficult to
heal due to high glucose levels, oxidative stress, and biofilm-associated microbial infection …

Promoting angiogenesis with mesoporous microcarriers through a synergistic action of delivered silicon ion and VEGF

K Dashnyam, GZ Jin, JH Kim, R Perez, JH Jang… - Biomaterials, 2017 - Elsevier
Angiogenic capacity of biomaterials is a key asset to drive vascular ingrowth during tissue
repair and regeneration. Here we design a unique angiogenic microcarrier based on sol-gel …

Thermo-sensitive nanomaterials: recent advance in synthesis and biomedical applications

P Sánchez-Moreno, J De Vicente, S Nardecchia… - Nanomaterials, 2018 - mdpi.com
Progress in nanotechnology has enabled us to open many new fronts in biomedical
research by exploiting the peculiar properties of materials at the nanoscale. The thermal …

Human organ rejuvenation by VEGF-A: Lessons from the skin

A Keren, M Bertolini, Y Keren, Y Ullmann, R Paus… - Science …, 2022 - science.org
Transplanting aged human skin onto young SCID/beige mice morphologically rejuvenates
the xenotransplants. This is accompanied by angiogenesis, epidermal repigmentation, and …

Big healthcare data analytics: Challenges and applications

C Lee, Z Luo, KY Ngiam, M Zhang, K Zheng… - Handbook of large-scale …, 2017 - Springer
Increasing demand and costs for healthcare, exacerbated by ageing populations and a
great shortage of doctors, are serious concerns worldwide. Consequently, this has …

Peptide-modified nano-bioactive glass for targeted immobilization of native VEGF

M Schumacher, P Habibović… - ACS Applied Materials & …, 2022 - ACS Publications
A limiting factor in large bone defect regeneration is the slow and disorganized formation of
a functional vascular network in the defect area, often resulting in delayed healing or implant …

The evaluation of functional small intestinal submucosa for abdominal wall defect repair in a rat model: Potent effect of sequential release of VEGF and TGF-β1 on host …

Z Liu, X Liu, L Bao, J Liu, X Zhu, X Mo, R Tang - Biomaterials, 2021 - Elsevier
Ineffective vessel penetration and extracellular matrix (ECM) remodeling are responsible for
the failure of porcine small intestinal submucosa (SIS)-repaired abdominal wall defects …

Nanoparticle-coated sutures providing sustained growth factor delivery to improve the healing strength of injured tendons

YL Zhou, QQ Yang, L Zhang, JB Tang - Acta Biomaterialia, 2021 - Elsevier
Tendon injuries are common diseases. The healing capacity of tendon is limited due to its
special composition of extra-cellular matrix and hypocellularity and hypovascularity. The …