Caspase-8 and caspase-9 functioned differently at different stages of the cyclic stretch-induced apoptosis in human periodontal ligament cells

Y Wu, D Zhao, J Zhuang, F Zhang, C Xu - PLoS One, 2016 - journals.plos.org
Background Human periodontal ligament (PDL) cells underwent apoptosis after mechanical
stretch loading. However, the exact signalling pathway remains unknown. This study aimed …

Pathogenicity of Plesiomonas shigelloides causing mass mortalities of largemouth bass (Micropterus salmoides) and its induced host immune response

Q Qian, Z Chen, J Xu, Y Zhu, W Xu, X Gao… - Fish & Shellfish …, 2023 - Elsevier
The outbreak of mass mortality of M. salmoides occurred in an aquaculture farm in Jiangsu
province of China, showing signs of skin ulceration and haemorrhages. The bacteria were …

Effect of infection with Aeromonas hydrophila on antioxidant capacity, inflammation response, and apoptosis proteins in Chinese mitten crab (Eriocheir sinensis)

N Zheng, N Wang, Z Wang, G Abdallah, B Zhang… - … and Physiology Part C …, 2022 - Elsevier
Aeromonas hydrophila (A. hydrophila) as a serious bacterial disease endangering
aquaculture and the Chinese mitten crabs (Eriocheir sinensis) industry. The present study …

[HTML][HTML] Chemosensitizing effect of Astragalus polysaccharides on nasopharyngeal carcinoma cells by inducing apoptosis and modulating expression of Bax/Bcl-2 …

Z Zhou, M Meng, H Ni - Medical science monitor: international …, 2017 - ncbi.nlm.nih.gov
Background Platinum-based chemotherapy is the most effective regimen for
nasopharyngeal carcinoma, which presents highly invasive and metastatic activity …

Carvacrol inhibits cadmium toxicity through combating against caspase dependent/independent apoptosis in PC12 cells

S Banik, M Akter, SEC Bondad, T Saito… - Food and Chemical …, 2019 - Elsevier
Carvacrol is a monoterpenic phenol found in essential oils, is considered a safe food
additive, and possesses various therapeutic properties. Numerous studies have also …

Effect and mechanism of Sorbus pohuashanensis (Hante) Hedl. flavonoids protect against arsenic trioxide-induced cardiotoxicity

X Yu, Z Wang, Z Shu, Z Li, Y Ning, K Yun, H Bai… - Biomedicine & …, 2017 - Elsevier
The cardiotoxicity of arsenic trioxide (ATO) limits its clinical application in cancer treatment.
Evidences suggest that sorbus has antioxidant activity and its consumption has been linked …

Ginger polysaccharide promotes myeloid‐derived suppressor cell apoptosis by regulating lipid metabolism

C Song, Y Ji, W Wang, N Tao - Phytotherapy Research, 2023 - Wiley Online Library
Recently, targeting myeloid‐derived suppressor cells (MDSCs) which mainly play an
immunosuppressive role in tumor microenvironment has become a hot spot in tumor …

Expression levels of caspase‐3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer

YL Huang, GH Zhang, Q Zhu, X Wu, LG Wu - Cancer Reports, 2022 - Wiley Online Library
Background Pyroptosis plays a dual role in the development of cancer and malignancy; as
such, it may potentially be a new target for cancer treatment. However, the inflammatory …

An Asparagus polysaccharide fraction inhibits MDSCs by inducing apoptosis through toll‐like receptor 4

W Zhang, W He, X Shi, X Li, Y Wang, M Hu… - Phytotherapy …, 2018 - Wiley Online Library
Despite decades of research, malignant tumors are extremely difficult to eliminate with
conventional methods. Although surgical resection potentially eradicates the problem, only a …

Polyphenolic Composition and Anti-Melanoma Activity of White Forsythia (Abeliophyllum distichum Nakai) Organ Extracts

TK Yoo, JS Kim, TK Hyun - Plants, 2020 - mdpi.com
Abeliophyllum distichum Nakai, commonly called white forsythia, is a monotypic genus
endemic to Korea. Although A. distichum is mainly used as an ornamental plant because of …