Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …

The genetic variants of HLAs (human leukocyte antigens) play a crucial role in the virus–
host interaction and pathology of COVID-19. The genetic variants of HLAs not only influence …

Background The COVID‐19 pandemic has had a profound global impact, with variations in
susceptibility, severity, and mortality rates across different regions. While many factors can …

We analyzed the association between HLA polymorphisms and susceptibility to SARS‐CoV‐
2 infection and disease severity. Genotyping data from a total of 9373 COVID‐19‐positive …

The T-cell immune response is a major determinant of effective SARS-CoV-2 clearance.
Here, using the recently developed T-CoV bioinformatics pipeline (https://t-cov. hse. ru) we …

Host genetic variability contributes to susceptibility to SARS‐CoV‐2 infection and COVID‐19
evolution and the role of HLA system has not clearly emerged, suggesting the involvement …

Objective To investigate the changes of Spike protein-HLA binding affinity profiles between
the Wuhan strain and two dominant variants, the Delta and the Omicron strains, among the …

Abstract According to the International Agency for Research on Cancer, breast cancer is
more common than lung cancer globally. By 2040, mortality from breast cancer will rise by …

The SARS-CoV-2 pandemic continues to pose a global threat. While its virulence has
subsided, it has persisted due to the continual emergence of new mutations. Although many …

Abstract Background Immigrants represented 21.8% of cases in a Spanish cohort of
hospitalised patients with COVID-19, a proportion exceeding the percentage of immigrants …