Introduction to the background, principles, and state of the art in suicide gene therapy

I Niculescu-Duvaz, CJ Springer - Molecular biotechnology, 2005 - Springer
Gene therapy is defined as a technology that aims to modify the genetic component of cells
to gain therapeutic benefits. Suicide gene therapy (or gene-directed enzyme prodrug …

Cancer gene therapy: combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect

K Lumniczky, G Sáfrány - Pathology & Oncology Research, 2006 - Springer
Current anti-cancer modalities such as surgery, chemo-and radiation therapies have only
limited success in cancer treatment. Gene therapy is a promising new tool to improve …

[PDF][PDF] Bystander-mediated regression of murine neuroblastoma via retroviral transfer of the HSV-TK gene

HS Cho, HR Lee, MK Kim - Journal of Korean medical …, 2004 - synapse.koreamed.org
Selective introduction of genes conferring chemosensitivity into proliferating tumor cells may
be used to treat cancer. We investigated the bystander effect of retrovirusmediated gene …

[HTML][HTML] 钙敏感受体在骨肉瘤中的研究进展

刘瑶, 赵勇 - Advances in Clinical Medicine, 2023 - hanspub.org
骨肉瘤(osteosarcoma, OS) 是来源于间充质的恶性骨肿瘤, 常侵犯长骨的干骺端,
特别是股骨远端和胫骨近端, 并易于血行肺转移. 随着新辅助化疗的进步, OS 患者5 …

Introduction to the background, principles, and state of the art in suicide gene therapy

I Niculescu-Duvaz, CJ Springer - Suicide Gene Therapy: Methods and …, 2004 - Springer
Chemotherapy is widely used with surgery and radiotherapy for the treatment of malignant
disease. Selectivity of most drugs for malignant cells remains elusive. Unfortunately, an …

Introduction to vectors for suicide gene therapy

CJ Springer - Suicide Gene Therapy: Methods and Reviews, 2004 - Springer
Suicide gene therapy requires vectors or vehicles capable of efficient and selective gene
delivery of the therapeutic genes to tumor cells. A number of vector systems has been …

Molecular imaging of therapeutic potential of reporter probes

B Thakur, S Chatterjee, S Chaudhury… - Current Drug …, 2015 - ingentaconnect.com
Success of medical treatments for any pathological disorders majorly depends on the
efficacy of the therapeutic molecules and their delivery to the target sites. Non-invasive …

骨肉瘤基因治疗研究进展

王桂龙, 向阳 - 医学研究杂志, 2007 - yxyjzz.cn
骨肉瘤是一种临床常见恶性骨肿瘤, 约占所有骨肿瘤的20%. 其恶性程度高, 好发于青少年,
易复发和转移, 预后较差. 随着分子生物学理论和技术水平的提高, 尤其是肿瘤分子生物学的发展 …

Das Tumorstroma als Angriffspunkt einer stammzellbasierten CCL5-Promoter/HSV-TK Suizidgentherapie in einem murinen Pankreastumormodell

C Zischek - 2011 - edoc.ub.uni-muenchen.de
Maligne Zellen wachsen in einem komplexen zellulären und extrazellulären Umfeld,
welches die Initiierung und Aufrechterhaltung des malignen Phänotyps bedeutend …

[引用][C] 骨肉瘤的治疗进展

孟琳, 李新志 - 医学综述, 2009