CRISPR/Cas9 in lepidopteran insects: Progress, application and prospects

JJ Li, Y Shi, JN Wu, H Li, G Smagghe, TX Liu - Journal of insect physiology, 2021 - Elsevier
Clustered regularly spaced short palindrome repeats (CRISPR) structure family forms the
acquired immune system in bacteria and archaea. Recent advances in CRISPR/Cas …

Cell death during complete metamorphosis

G Tettamanti, M Casartelli - Philosophical Transactions of …, 2019 - royalsocietypublishing.org
In insects that undergo complete metamorphosis, cell death is essential for reshaping or
removing larval tissues and organs, thus contributing to formation of the adult's body …

Toward a CRISPR-Cas9-Based Gene Drive in the Diamondback Moth Plutella xylostella

X Xu, T Harvey-Samuel, HA Siddiqui, JXD Ang… - The CRISPR …, 2022 - liebertpub.com
Promising to provide powerful genetic control tools, gene drives have been constructed in
multiple dipteran insects, yeast, and mice for the purposes of population elimination or …

Deletion of the Bombyx mori odorant receptor co-receptor (BmOrco) impairs olfactory sensitivity in silkworms

Q Liu, W Liu, B Zeng, G Wang, D Hao… - Insect Biochemistry and …, 2017 - Elsevier
Olfaction plays an essential role in many important insect behaviors such as feeding and
reproduction. To detect olfactory stimuli, an odorant receptor co-receptor (Orco) is required …

The FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyx mori

B Zeng, Y Huang, J Xu, T Shiotsuki, H Bai… - Journal of Biological …, 2017 - ASBMB
Forkhead box O (FOXO) functions as the terminal transcription factor of the insulin signaling
pathway and regulates multiple physiological processes in many organisms, including …

A salivary GMC oxidoreductase of Manduca sexta re-arranges the green leaf volatile profile of its host plant

YH Lin, JJM Silven, N Wybouw, RA Fandino… - Nature …, 2023 - nature.com
Green leaf volatiles (GLVs) are short-chain oxylipins that are emitted from plants in response
to stress. Previous studies have shown that oral secretions (OS) of the tobacco hornworm …

20-Hydroxyecdysone (20E) primary response gene E75 isoforms mediate steroidogenesis autoregulation and regulate developmental timing in Bombyx

K Li, L Tian, Z Guo, S Guo, J Zhang, SH Gu… - Journal of Biological …, 2016 - ASBMB
The temporal control mechanisms that precisely control animal development remain largely
elusive. The timing of major developmental transitions in insects, including molting and …

Depletion of juvenile hormone esterase extends larval growth in Bombyx mori

Z Zhang, X Liu, T Shiotsuki, Z Wang, X Xu… - Insect Biochemistry and …, 2017 - Elsevier
Two major hormones, juvenile hormone (JH) and 20-hydroxyecdysone (20E), regulate
insect growth and development according to their precisely coordinated titres, which are …

Transgenic clustered regularly interspaced short palindromic repeat/Cas9-mediated viral gene targeting for antiviral therapy of Bombyx mori nucleopolyhedrovirus

S Chen, C Hou, H Bi, Y Wang, J Xu, M Li… - Journal of …, 2017 - Am Soc Microbiol
We developed a novel antiviral strategy by combining transposon-based transgenesis and
the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated …

Sexually dimorphic traits in the silkworm, Bombyx mori, are regulated by doublesex

J Xu, S Zhan, S Chen, B Zeng, Z Li, AA James… - Insect biochemistry and …, 2017 - Elsevier
The DM domain genes, doublesex (dsx) in insects, or their structural homologs, male
abnormal 3 (mab-3) in nematodes and Dmrt1 (doublesex and mab-3-related transcription …