Lung cancer is the most common cancer worldwide. Treatment options for lung cancer
include surgery, radiation therapy, chemotherapy, molecularly targeted therapy including …

Actins and tubulins are abundant cytoskeletal proteins that support diverse cellular
processes. Owing to the unique properties of these filament-forming proteins, an intricate …

Prefoldin is a cochaperone, present in all eukaryotes, that cooperates with the chaperonin
CCT. It is known mainly for its functional relevance in the cytoplasmic folding of actin and …

Cellular functions are largely performed by proteins. Defects in the production, folding, or
removal of proteins from the cell lead to perturbations in cellular functions that can result in …

Prefoldin (PFDN) is a co-chaperone protein that is primarily known for its classic cytoplasmic
functions in the folding of actin and tubulin monomers during cytoskeletal assembly. Here …

The correct folding is a key process for a protein to acquire its functional structure and
conformation. Prefoldin is a well-known chaperone protein that regulates the correct folding …

Tubulin, the most abundant axonemal protein, is extensively modified by several highly
conserved post-translational mechanisms including acetylation, detyrosination …

Axons are the narrow, up-to-meter long cellular processes of neurons that form the
biological cables wiring our nervous system. Most axons must survive for an organism's …

Huntington disease is caused by cell death after the expansion of polyglutamine (polyQ)
tracts longer than∼ 40 repeats encoded by exon 1 of the huntingtin (HTT) gene. Prefoldin is …

Prefoldin subunits (PFDN), primarily known for co-chaperone function associated with
cytoskeletal rearrangement, have been found involved in epithelial–mesenchymal transition …